J Endod:牙髓再生可作为未发育成熟牙齿非手术再治疗的生物疗法

2019-11-24 lishiting MedSci原创

牙髓再生(RET)的目的是为了使牙髓坏死的未发育完成牙齿再生牙髓牙本质复合物。目前为止,还未见再治疗牙齿采用RET的论述。这篇文章报道的是已行牙髓治疗的未发育完成牙齿实施RET的长期疗效观察的病例。

牙髓再生(RET)的目的是为了使牙髓坏死的未发育完成牙齿再生牙髓牙本质复合物。目前为止,还未见再治疗牙齿采用RET的论述。这篇文章报道的是已行牙髓治疗的未发育完成牙齿实施RET的长期疗效观察的病例。

这篇报道选取的牙齿为已行牙髓治疗的未发育完成牙齿并出现治疗失败的症状/征兆。在局部麻醉和橡皮樟隔离患牙后,在未使用化学溶剂情况下取出根管内充填物。使用EndoVac (Kerr Endodontics, Culver City, CA)和6%次氯酸钠溶液 冲洗根管,将含有甲硝唑和环丙沙星的糊剂混合物至于根管内封药4周。第2次复诊时,使用17% EDTA去除根管内抗菌药物。随后根管内诱导出血,并放置SynOss Putty (Collagen Matrix Inc, Oakland, NJ)。生物陶瓷类材料至于SynOss Putty上方,第3次复诊时对牙齿进行修复。

结果显示,文章共纳入了4名患者的5颗牙齿。患者的年龄从14至46岁。复诊检查时间在术后20至72个月,平均为54.4个月。根尖开放的大小为1-3.7 mm。复诊时所有牙齿均行使功能且无任何症状。所有的根尖损伤均被部分或完全的根管钙化取代,并且所有牙齿均展现出部分的或完全根尖孔闭合。

结论:RET是非手术再治疗未发育成熟牙齿的一种可行方法。这篇文章为牙髓再生的应用添加了一项全新领域。

原始出处:

Cymerman JJ, Nosrat A. Regenerative Endodontic Treatment as a Biologically Based Approach for Non-Surgical Retreatment of Immature Teeth. J Endod. 2019 Nov 15. pii: S0099-2399(19)30749-6. doi: 10.1016/j.joen.2019.10.010.

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    2020-01-02 jxrzshh
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    2019-11-26 neurowu
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    2019-11-26 zhouqu_8
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    2019-11-26 whmdzju
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    2019-11-24 14794e5bm67(暂无昵称)

    非常好的研究,受益

    0

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