JCO:乳腺癌术前使用MRI或许会导致过度诊断

2015-12-03 zhaozhou 译 MedSci原创

 术前乳腺核磁成像(MRI)已经被越来越多地用于乳腺癌诊断当中了。但是MRI的常规使用仍然处于争议当中。MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被今早的治疗,从而改善患者的存活时间。但是,使用MRI检测长期CBC的影响尚不明确。为此,研究人员分析了MRI的使用是否可以降低CBC的发生以及用于患CBC女性的2-4期疾病的检测。&nbs

术前乳腺核磁成像(MRI)已经被越来越多地用于乳腺癌诊断当中了。但是MRI的常规使用仍然处于争议当中。MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被尽早地治疗,从而改善患者的存活时间。但是,使用MRI检测长期CBC的影响尚不明确。为此,研究人员分析了MRI的使用是否可以降低CBC的发生以及用于患CBC女性的2-4期疾病的检测。
 

研究人员分析了SEER-Medicare数据库,评价了总体的、同时期的(在首次癌症诊断后6个月内)以及随后的不同时期的CBC发生情况。这些妇女均是在2004年到2009年间被诊断为1或2期乳腺癌,并且被观察至2011年。在这38971名妇女中,6377名(16.4%)接受了术前MRI。相对于没有经过术前MRI检测的女性,术前使用了MRI与更高的同时期CBC检测率显著相关。但是随后的CBC检测率更低。然而,接受了术前MRI的女性五年累积CBC发病率仍然显著高于未接受MRI的女性。
 
此项研究表明,MRI的使用可以增加同时期的CBC检测率,并且没有被随后的CBC发生率所抵消。这说明乳腺癌女性术前使用MRI或许会导致过度诊断。

原始出处:

Shi-Yi Wang et al. Preoperative Breast Magnetic Resonance Imaging and Contralateral Breast Cancer Occurrence Among Older Women With Breast Cancer. JOURNAL OF CLINICAL ONCOLOGY. Published Ahead of Print on November 30, 2015 as 10.1200/JCO.2015.62.9741

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  1. [GetPortalCommentsPageByObjectIdResponse(id=103165, encodeId=08b810316549, content=那么什么时候要用MRI呢?过度诊断并不代表过度治疗吧?, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160616/IMG5762A3665DC7B3997.jpg, createdBy=df0a1649089, createdName=ys2323, createdTime=Wed Aug 24 17:19:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1891238, encodeId=57e4189123838, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Tue Mar 29 17:17:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49071, encodeId=b549490e15c, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:01:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45450, encodeId=2ef14545092, content=MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被尽早地治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:29:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45449, encodeId=e74645449a0, content=此项研究表明,MRI的使用可以增加同时期的CBC检测率,并且没有被随后的CBC发生率所抵消。这说明乳腺癌女性术前使用MRI或许会导致过度诊断。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:28:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2016-08-24 ys2323

    那么什么时候要用MRI呢?过度诊断并不代表过度治疗吧?

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=103165, encodeId=08b810316549, content=那么什么时候要用MRI呢?过度诊断并不代表过度治疗吧?, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160616/IMG5762A3665DC7B3997.jpg, createdBy=df0a1649089, createdName=ys2323, createdTime=Wed Aug 24 17:19:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1891238, encodeId=57e4189123838, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Tue Mar 29 17:17:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49071, encodeId=b549490e15c, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:01:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45450, encodeId=2ef14545092, content=MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被尽早地治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:29:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45449, encodeId=e74645449a0, content=此项研究表明,MRI的使用可以增加同时期的CBC检测率,并且没有被随后的CBC发生率所抵消。这说明乳腺癌女性术前使用MRI或许会导致过度诊断。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:28:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2016-03-29 lidong40
  3. [GetPortalCommentsPageByObjectIdResponse(id=103165, encodeId=08b810316549, content=那么什么时候要用MRI呢?过度诊断并不代表过度治疗吧?, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160616/IMG5762A3665DC7B3997.jpg, createdBy=df0a1649089, createdName=ys2323, createdTime=Wed Aug 24 17:19:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1891238, encodeId=57e4189123838, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Tue Mar 29 17:17:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49071, encodeId=b549490e15c, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:01:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45450, encodeId=2ef14545092, content=MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被尽早地治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:29:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45449, encodeId=e74645449a0, content=此项研究表明,MRI的使用可以增加同时期的CBC检测率,并且没有被随后的CBC发生率所抵消。这说明乳腺癌女性术前使用MRI或许会导致过度诊断。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:28:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=103165, encodeId=08b810316549, content=那么什么时候要用MRI呢?过度诊断并不代表过度治疗吧?, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160616/IMG5762A3665DC7B3997.jpg, createdBy=df0a1649089, createdName=ys2323, createdTime=Wed Aug 24 17:19:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1891238, encodeId=57e4189123838, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Tue Mar 29 17:17:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49071, encodeId=b549490e15c, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:01:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45450, encodeId=2ef14545092, content=MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被尽早地治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:29:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45449, encodeId=e74645449a0, content=此项研究表明,MRI的使用可以增加同时期的CBC检测率,并且没有被随后的CBC发生率所抵消。这说明乳腺癌女性术前使用MRI或许会导致过度诊断。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:28:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2015-12-10 jetleo

    MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被尽早地治疗

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=103165, encodeId=08b810316549, content=那么什么时候要用MRI呢?过度诊断并不代表过度治疗吧?, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160616/IMG5762A3665DC7B3997.jpg, createdBy=df0a1649089, createdName=ys2323, createdTime=Wed Aug 24 17:19:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1891238, encodeId=57e4189123838, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Tue Mar 29 17:17:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49071, encodeId=b549490e15c, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:01:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45450, encodeId=2ef14545092, content=MRI的一种用途就是筛查对侧乳腺癌(CBC)。通过使用MRI,潜伏的CBC或许能被检测出来,并且被尽早地治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:29:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45449, encodeId=e74645449a0, content=此项研究表明,MRI的使用可以增加同时期的CBC检测率,并且没有被随后的CBC发生率所抵消。这说明乳腺癌女性术前使用MRI或许会导致过度诊断。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Thu Dec 10 13:28:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2015-12-10 jetleo

    此项研究表明,MRI的使用可以增加同时期的CBC检测率,并且没有被随后的CBC发生率所抵消。这说明乳腺癌女性术前使用MRI或许会导致过度诊断。

    0

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