J Affect Disord:在中国,首发抑郁症患者躯体症状与自杀意念的关系

2018-12-17 MedSci MedSci原创

躯体症状普遍存在于严重抑郁症(MDD)的患者中,并且通常与高自杀风险相关。然而,在MDD中,哪些躯体症状为自杀意念(SI)的重要风险因素仍然知之甚少。本研究纳入了来自全国抑郁症症状调查的第一期MDD患者中的217名患者。建立医生评定评估问卷以评估抑郁相关的躯体症状,并进行逐步逻辑回归分析以探讨躯体症状与SI之间的关系。结果显示,首发MDD患者的当前SI患病率较高(50.87%),而未观察到明显的性

躯体症状普遍存在于严重抑郁症(MDD)的患者中,并且通常与高自杀风险相关。然而,在MDD中,哪些躯体症状为自杀意念(SI)的重要风险因素仍然知之甚少。

本研究纳入了来自全国抑郁症症状调查的第一期MDD患者中的217名患者。建立医生评定评估问卷以评估抑郁相关的躯体症状,并进行逐步逻辑回归分析以探讨躯体症状与SI之间的关系。

结果显示,首发MDD患者的当前SI患病率较高(50.87%),而未观察到明显的性别差异(53.32% VS. 49.26%,P = 0.076)。此外,具有更多躯体症状的患者引发SI的风险更高,逐步逻辑回归分析表明年龄(β= -0.020,P <0.001),难以言说的躯体不适(β= 0.356,P = 0.001),感觉系统不适(β= 0.707,P = 0.000),其他疼痛情况(β= 0.434,P <0.001),晚期失眠(β= 0.267,P = 0.008),睡眠过度(β= 0.936,P <0.001),体重减轻(β= 0.272,P = 0.006),性欲低下(β= 0.513,P = P <0.001)与首发中国严重抑郁症患者的当前SI密切相关。

综上所述,该研究结果表明,在首发MDD中,躯体症状与SI密切相关。提示临床医生在实践中应注意患者的躯体症状。

原始出处:

Fang X, Zhang C, et al., The association between somatic symptoms and suicidal ideation in Chinese first-episode majordepressive disorder. J Affect Disord. 2018 Oct 17;245:17-21. doi: 10.1016/j.jad.2018.10.110. 

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    2019-08-09 cmsvly
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    2019-03-28 chenwq08
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1784408, encodeId=bdc91e84408e1, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Fri Aug 09 00:31:00 CST 2019, time=2019-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1776849, encodeId=53cb1e76849af, content=<a href='/topic/show?id=3484932549b' target=_blank style='color:#2F92EE;'>#躯体症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93254, encryptionId=3484932549b, topicName=躯体症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=914539043288, createdName=yourmama, createdTime=Sat Mar 23 18:31:00 CST 2019, time=2019-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779425, encodeId=a0d91e79425ef, content=<a href='/topic/show?id=48dc20680a' target=_blank style='color:#2F92EE;'>#Affect#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2068, encryptionId=48dc20680a, topicName=Affect)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Thu Mar 28 09:31:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012878, encodeId=02d520128e832, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Aug 11 03:31:00 CST 2019, time=2019-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988593, encodeId=2a4d198859324, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Fri Oct 04 06:31:00 CST 2019, time=2019-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956142, encodeId=8f4d19561429e, content=<a href='/topic/show?id=0103862137f' target=_blank style='color:#2F92EE;'>#自杀意念#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86213, encryptionId=0103862137f, topicName=自杀意念)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erCiat0j36p5MejdM9yCLtcVcY8WS5VIKuCMqXFNs56U6iacZib5CJvh6mVxGERicM6ZAkl91jMgpcDrw/132, createdBy=37622500012, createdName=ms2999106592497887, createdTime=Fri May 17 02:31:00 CST 2019, time=2019-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355681, encodeId=0d95355681c3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Dec 17 20:24:46 CST 2018, time=2018-12-17, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1784408, encodeId=bdc91e84408e1, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Fri Aug 09 00:31:00 CST 2019, time=2019-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1776849, encodeId=53cb1e76849af, content=<a href='/topic/show?id=3484932549b' target=_blank style='color:#2F92EE;'>#躯体症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93254, encryptionId=3484932549b, topicName=躯体症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=914539043288, createdName=yourmama, createdTime=Sat Mar 23 18:31:00 CST 2019, time=2019-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779425, encodeId=a0d91e79425ef, content=<a href='/topic/show?id=48dc20680a' target=_blank style='color:#2F92EE;'>#Affect#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2068, encryptionId=48dc20680a, topicName=Affect)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Thu Mar 28 09:31:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012878, encodeId=02d520128e832, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Aug 11 03:31:00 CST 2019, time=2019-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988593, encodeId=2a4d198859324, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Fri Oct 04 06:31:00 CST 2019, time=2019-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956142, encodeId=8f4d19561429e, content=<a href='/topic/show?id=0103862137f' target=_blank style='color:#2F92EE;'>#自杀意念#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86213, encryptionId=0103862137f, topicName=自杀意念)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erCiat0j36p5MejdM9yCLtcVcY8WS5VIKuCMqXFNs56U6iacZib5CJvh6mVxGERicM6ZAkl91jMgpcDrw/132, createdBy=37622500012, createdName=ms2999106592497887, createdTime=Fri May 17 02:31:00 CST 2019, time=2019-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355681, encodeId=0d95355681c3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Dec 17 20:24:46 CST 2018, time=2018-12-17, status=1, ipAttribution=)]
    2018-12-17 医者仁心5538

    学习了

    0