Obes Rev:运动训练对肥胖或超重成年人的心脏代谢健康的影响

2021-05-10 MedSci原创 MedSci原创

运动训练可有效改善超重或肥胖的成年人的心脏代谢健康,以及其他相关并发症(如脂肪肝)

肥胖是一种日益严重的多因素的全球性疾病和公共卫生问题。肥胖的大流行性扩张同时伴随着许多相关合并症的增加,而这些合并症本身就是血管风险增加的决定因素。

这是一项系统性回顾性分析,旨在评估运动干预计划对超重或肥胖的成人患者的心脏代谢健康指标的影响。

研究人员检索了三个电子数据库,筛选纳入了超重或肥胖的成年人并予以了运动训练干预的随机对照试验(RCT)。采用随机效应Meta分析对比了运动与对照对受试者血压、胰岛素抵抗(胰岛素抵抗的稳态模型,HOMA-IR)以及肝内脂肪的磁共振测量的影响。

运动干预对收缩压的影响

总体上,共筛选到了54篇符合纳入条件的研究。运动训练可明显降低受试者的收缩压(平均差[MD] -2.95 mmHg,95% CI -4.22~-1.68,p<0.00001, I2=63%;60个研究臂)和舒张压(MD -1.93 mmHg,95%CI -2.73~-1.13,p<0.00001, I2=54%;58个研究臂)。

运动干预对舒张压的影响

在高血压患者中,运动干预也可明显降低其收缩压和舒张压。此外,运动干预还可显著减弱胰岛素抵抗效应(标准化MD[SMD] -0.34,95%CI -0.49~-0.18,p<0.00001, I2=48%;37个研究臂),而且在2型糖尿病患者亚组中该效应更明显(SMD -0.50,95%CI -0.83~-0.17,p=0.003,I2=39%)。

运动干预对肝内脂肪的影响

运动干预后,受试者的肝内脂肪量明显减少(SMD -0.59,95%CI -0.78~-0.41, p<0.00001, I2=0%),高强度间歇训练的效果更为显著。

综上所述,运动训练可有效改善超重或肥胖的成年人的心脏代谢健康,以及其他相关并发症(如脂肪肝)

原始出处:

Battista Francesca,Ermolao Andrea,van Baak Marleen A et al. Effect of exercise on cardiometabolic health of adults with overweight or obesity: Focus on blood pressure, insulin resistance, and intrahepatic fat-A systematic review and meta-analysis. Obes Rev, 2021, undefined: e13269. https://doi.org/10.1111/obr.13269

 

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    2021-05-11 王静6093

    必须运动了!

    0

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    2021-05-10 SR~young海东

    不能再胖了

    0

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