JAHA:急性缺血性卒中后急性心肌梗塞的五年风险

2020-12-30 MedSci原创 MedSci原创

AIS患者AMI的发生率相对较低,并且在卒中发生后第一年发生率最高。CHD是卒中后AMI的最主要危险因素,其风险大约升高5倍。

在不同种族的大型队列研究中,尚没有明确急性缺血性卒中(AIS)患者急性心肌梗死(AMI)的长期发生率。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员确定多中心全国卒中登记中心登记的AIS患者组建AIS患者的前瞻性队列,以通过与国家健康保险服务索赔数据库进行链接,随访了AMI的发生率。根据预先定义的人口统计学亚组、卒中亚型、冠心病(CHD)病史以及已知的CHD危险因素,估算5年累积发病率和年度风险。

该研究共分析了11720名AIS患者,AMI的5年累积发生率为2.0%。事件发生后的第一年,年度风险最高(1.1%),第二至第五年的年度风险则较低(0.16%至0.27%)。在亚组中,伴有冠心病史的人群第一年的年度风险最高(4.1%),而没有冠心病史的人群第一年的风险最高(0.8%)。与大血管闭塞(2.2%)或心脏栓塞(2.4%)亚型相比,小血管闭塞亚型的发生率相对较低(0.8%)。在多变量分析中,冠心病病史(风险比为2.84;95%CI为2.01-3.93)是AIS发生后AMI最强的独立预测因素。

由此可见,AIS患者AMI的发生率相对较低,并且在卒中发生后第一年发生率最高。CHD是卒中后AMI的最主要危险因素,其风险大约升高5倍

原始出处:

Keon‐Joo Lee.et al.Five‐Year Risk of Acute Myocardial Infarction After Acute Ischemic Stroke in Korea.J AM HEART ASSOC.2020.https://www.ahajournals.org/doi/10.1161/JAHA.120.018807

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    2021-01-01 zhaohui6731
  6. [GetPortalCommentsPageByObjectIdResponse(id=1893346, encodeId=fcbc1893346b8, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Wed Nov 17 04:58:25 CST 2021, time=2021-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671416, encodeId=582b16e1416ba, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Sun Jun 27 03:58:25 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806417, encodeId=6906180641e09, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Mon Sep 13 04:58:25 CST 2021, time=2021-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2039580, encodeId=1a672039580b8, content=<a href='/topic/show?id=ea4024183ac' target=_blank style='color:#2F92EE;'>#五年风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24183, encryptionId=ea4024183ac, topicName=五年风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Fri Oct 15 19:58:25 CST 2021, time=2021-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268382, encodeId=1ac112683828e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Fri Jan 01 11:58:25 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1508688, encodeId=6e3b150868870, content=<a href='/topic/show?id=e64b52283a7' target=_blank style='color:#2F92EE;'>#急性心肌梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52283, encryptionId=e64b52283a7, topicName=急性心肌梗塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bbe29994869, createdName=zhty5340, createdTime=Fri Jan 01 11:58:25 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026734, encodeId=5ce41026e34ff, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Wed Dec 30 23:58:25 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912351, encodeId=ab4291235118, content=第一年发生率最高吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=42245448959, createdName=ms7000000261672610, createdTime=Wed Dec 30 21:52:45 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912346, encodeId=0b3d91234670, content=CHD是卒中后AMI的最主要危险因素,其风险大约升高5倍。, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Dec 30 21:51:03 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
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    2020-12-30 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2020-12-30 ms7000000261672610

    第一年发生率最高吗

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1893346, encodeId=fcbc1893346b8, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Wed Nov 17 04:58:25 CST 2021, time=2021-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671416, encodeId=582b16e1416ba, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Sun Jun 27 03:58:25 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806417, encodeId=6906180641e09, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Mon Sep 13 04:58:25 CST 2021, time=2021-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2039580, encodeId=1a672039580b8, content=<a href='/topic/show?id=ea4024183ac' target=_blank style='color:#2F92EE;'>#五年风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24183, encryptionId=ea4024183ac, topicName=五年风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Fri Oct 15 19:58:25 CST 2021, time=2021-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268382, encodeId=1ac112683828e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Fri Jan 01 11:58:25 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1508688, encodeId=6e3b150868870, content=<a href='/topic/show?id=e64b52283a7' target=_blank style='color:#2F92EE;'>#急性心肌梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52283, encryptionId=e64b52283a7, topicName=急性心肌梗塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bbe29994869, createdName=zhty5340, createdTime=Fri Jan 01 11:58:25 CST 2021, time=2021-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026734, encodeId=5ce41026e34ff, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Wed Dec 30 23:58:25 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912351, encodeId=ab4291235118, content=第一年发生率最高吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=42245448959, createdName=ms7000000261672610, createdTime=Wed Dec 30 21:52:45 CST 2020, time=2020-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=912346, encodeId=0b3d91234670, content=CHD是卒中后AMI的最主要危险因素,其风险大约升高5倍。, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Dec 30 21:51:03 CST 2020, time=2020-12-30, status=1, ipAttribution=)]
    2020-12-30 三生有幸9135

    CHD是卒中后AMI的最主要危险因素,其风险大约升高5倍。

    0

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