Cochrane Library:ω-3脂肪酸有望作为治疗抑郁症的新药物

2015-11-08 chenshuo 译 MedSci原创

近年来,由于在既往的研究中发现ω-3脂肪酸能降低心脏病的风险和降低人体胆固醇,目前它已经成为美国最受欢迎的营养补充剂。由于ω-3脂肪酸是天然存在于含油多的鱼类中,包括金枪鱼和海鲜,以及一些坚果和种子。因此,ω-3脂肪酸可以通过饮食来补充。最近,根据Cochrane Library上最新的一篇综述表明,ω-3脂肪酸不仅对人体健康有有益,同时,还有可能对治疗抑郁症有重要的作用。来自英国伯恩茅斯大学的阿

近年来,由于在既往的研究中发现ω-3脂肪酸能降低心脏病的风险和降低人体胆固醇,目前它已经成为美国最受欢迎的营养补充剂。由于ω-3脂肪酸是天然存在于含油多的鱼类中,包括金枪鱼和海鲜,以及一些坚果和种子。因此,ω-3脂肪酸可以通过饮食来补充。



最近,根据Cochrane Library上最新的一篇综述表明,ω-3脂肪酸不仅对人体健康有有益,同时,还有可能对治疗抑郁症有重要的作用。

来自英国伯恩茅斯大学的阿普尔顿博士与其研究团队为了进一步探讨ω-3脂肪酸对治疗抑郁症的作用,进行了26项回顾性随机临床试验,共涉及1458名参与者。研究结果发表在Cochrane Library上。

参与者被随机分为试验组和对照组,实验组予服用ω-3脂肪酸,对照组予服用治疗抑郁症的安慰剂作为对照。

经过后期的随访观察研究人员发现,与服用安慰剂的对照组相比,那些接受补充ω-3脂肪酸的小组成员抑郁症症状评分有所降低。然而,研究小组成员认为,该结果并未能真正地说明ω-3脂肪酸在治疗抑郁症的作用,毕竟他们的样本量是非常小的,同时还有一些其他的因素可能也对试验的结果产生了影响。

“虽然我们在试验中发现了ω-3脂肪酸与安慰剂组相比,对抑郁症患者产生了积极的作用,但我们目前尚未有充足的证据证明ω-3脂肪酸所起的作用。然而,对于患有抑郁症的患者,我们仍可以使用ω-3脂肪酸对其进行治疗,只有这样我们才能为患者带来更多的治疗方案。”阿普尔顿博士说。

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