高龄患者骨科术毕出现肺栓塞致呼吸心跳骤停1例

2018-05-03 骆常强 高健 潘玮 麻醉安全与质控

患者,男,85岁,体质量84kg,身高175cm。

【一般资料】

患者,男,85岁,体质量84kg,身高175cm。

【主诉】

因右大腿肿物进行性增大1月,来甘肃省肿瘤医院就诊,门诊以“右大腿肿物待查”收住院,

【现病史】

行“右大腿巨大肿物切除及血管神经探查术”。术前2周患者在外院就诊,行MRI检查提示:右大腿外后缘巨大占位(15cm×15cm),合并血栓形成。给予溶栓治疗。用药剂量不详。后因肿痛未缓解,进一步医治来甘肃省肿瘤医院就诊。

【既往史】

患者有冠心病史,心脏支架术后7年,有胃出血、胆囊手术及输血史。否认高血压糖尿病、肝炎、肾炎等。

【辅助检查】

血常规:WBC3.43×109,RBC3.47×1012,Hb107g/L,Hct30.5%。PLT145×109,生化检查:凝血酶原时间11.9s,消化部分凝血酶原时间33.3s,纤维蛋白原3.9/L,凝血酶时间20.1s,D-二聚体7.3m/L,纤维蛋白降解产物20.20μg/mL。B超提示,双下肢动脉粥样硬化并粥样硬化多发斑块形成;右侧胭静脉及胫后静脉血栓形成(不完全栓塞);左侧颈动脉粥样硬化斑块形成;心脏B超,EF64%,左房内经增大,主动脉瓣钙化,左室收缩功能正常,舒张功能减低,主动脉瓣、二尖瓣及三尖瓣少量返流,肺功能正常。

【治疗】

入手术室,建立静脉通道,置深静脉,测BP140/92mmHg,HR78次/min,RR12次/min,SPO292%,面罩去氮给氧,静推咪唑安定2mg,芬太尼0.2mg,丙泊酚50mg,维库溴铵10mg,快速诱导,顺利插管。静脉丙泊酚靶控输注及吸入异氟醚维持麻醉,间断给予肌松药维库溴铵和镇痛药芬太尼。术中患者BP110~130/60~80mmHg,HR60~80次/min,SpO2100%,PETCO235~38mmHg。手术进行3h,测血气,PH7.338,PCO240.5mmHg,PO2194mmHg,Hb67/L,Hct20.5%,K+4.3mmol/L,Na+140mmol/L,Cl-115mmol/L,Ca2+1.07mmol/L,Glu10mmol/L,cLac0.7mmol/L,经过100min,术毕,BP122/80mmHg,HR70次/min,SpO2100%。术中输晶体液3150mL,胶体液1000mL,输红细胞3.5U,血浆300mL,出血1800mL,尿量1500mL。患者12:35手术结束,抬到转运床,途中呼吸囊辅助呼吸,于12:40带管人ICU。交接时,BP110/72mmHg,HR100次/min,RR16次/min(机控),SpO2100%。12:45,患者SpO2下降至23%,颜面、口唇发绀,皮肤湿冷,呈花斑样改变,大动脉未触及,双测瞳孔不等大,对光反射迟钝,立即心外按压,1mg肾上腺素静注,患者心脏复跳,大动脉搏动可触及,HR132次/Imn,BP209/98_Hg,SpO2逐渐升至100%。即查血气pH7.041,PCO276.8mmHg,PO270.9mmHg,Hb10g/L,Hct30.7%,K+5.6mmol/L,Na+140mmol/L,Cl-114mmol/L,Ca2+1.23mmO]/L,Glu13.1mmO]/L,cLac3.8mmol/L,患者仍处于麻醉状态,双侧瞳孔不等大,右侧打开困难(追问病史,家属诉既往右眼有硫酸灼伤史),左侧瞳孔对光反应灵敏,双肺呼吸音粗,未闻及干湿性啰音,HR130次/min,律齐,未闻及杂音。复苏成功后,积极给予头戴冰帽,降颅内压,纠酸,扩容,纠正酸碱平衡紊乱等对症处理。13:43血常规回报,WBC8.13×109/L,RBC3.03×1012/L,Hb94g/L,Hct26.2%,PLT188×109;血生化回报,血清总蛋白39.4g/L,血清白蛋白27.2g/L,血清球蛋白12.2g/L,血糖17.86mmol/L,尿素氣3.66mmol/L,CO2结合力19.9mmol/L,血肌酐66#mol/L,血淀粉酶24U/L,K+4.03mmol/L,Na+134.9mmol/L,Cl-105.8mmol/L,Ca2+2.18mmol/L。14:14回报,凝血酶原时间11.9M消化部分凝血酶原时间28.2M纤维蛋白原3.0g/L,凝血酶时间19.1s,D-二聚体2.71m/L,纤维蛋白降解产物8.2μg/mL。在ICU经继续呼吸支持,保护脏器功能,纠正低蛋白血症,维持内环境稳定,并予营养支持等治疗,患者生命体征平稳后,给予吸痰,拔管,次日9时安返病房。在病房B超复查,右侧胭静脉及胫后静脉血栓形成消失,6d后B超再次复查,右侧肌间静脉血栓形成(不完全栓塞)。

原始出处:

骆常强, 高健, 潘玮. 高龄患者骨科术毕出现肺栓塞致呼吸心跳骤停1例[J]. 麻醉安全与质控, 2017, 1(3):146-147.

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    2018-06-22 12324fb8m77暂无昵称

    学习了.谢谢分享

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun May 06 22:34:27 CST 2018, time=2018-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312176, encodeId=3bf73121e603, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sat May 05 08:00:12 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416068, encodeId=a66f1416068e3, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481339, encodeId=fa2e14813394f, content=<a href='/topic/show?id=60a1519e294' target=_blank style='color:#2F92EE;'>#心跳骤停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51972, encryptionId=60a1519e294, topicName=心跳骤停)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=61de7776499, createdName=ms7474195563676018, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312092, encodeId=d8013120927a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat May 05 05:55:00 CST 2018, time=2018-05-05, status=1, ipAttribution=)]
  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun Jun 03 15:21:11 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313413, encodeId=149731341374, content=好文献.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Wed May 09 07:10:02 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312633, encodeId=949731263319, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun May 06 22:34:27 CST 2018, time=2018-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312176, encodeId=3bf73121e603, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sat May 05 08:00:12 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416068, encodeId=a66f1416068e3, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481339, encodeId=fa2e14813394f, content=<a href='/topic/show?id=60a1519e294' target=_blank style='color:#2F92EE;'>#心跳骤停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51972, encryptionId=60a1519e294, topicName=心跳骤停)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=61de7776499, createdName=ms7474195563676018, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312092, encodeId=d8013120927a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat May 05 05:55:00 CST 2018, time=2018-05-05, status=1, ipAttribution=)]
    2018-06-03 wqkm

    ^_^^_^^_^^_^

    0

  5. 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topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481339, encodeId=fa2e14813394f, content=<a href='/topic/show?id=60a1519e294' target=_blank style='color:#2F92EE;'>#心跳骤停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51972, encryptionId=60a1519e294, topicName=心跳骤停)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=61de7776499, createdName=ms7474195563676018, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312092, encodeId=d8013120927a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat May 05 05:55:00 CST 2018, time=2018-05-05, status=1, ipAttribution=)]
    2018-05-09 张新亮1853311252142e2fm

    好文献.学习了

    0

  6. 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topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481339, encodeId=fa2e14813394f, content=<a href='/topic/show?id=60a1519e294' target=_blank style='color:#2F92EE;'>#心跳骤停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51972, encryptionId=60a1519e294, topicName=心跳骤停)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=61de7776499, createdName=ms7474195563676018, createdTime=Sat May 05 07:46:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312092, encodeId=d8013120927a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat May 05 05:55:00 CST 2018, time=2018-05-05, status=1, ipAttribution=)]
    2018-05-06 wqkm

    ^_^^_^^_^

    0

  7. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat May 05 05:55:00 CST 2018, time=2018-05-05, status=1, ipAttribution=)]
    2018-05-05 张新亮1853311252142e2fm

    好文献学习了

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat May 05 05:55:00 CST 2018, time=2018-05-05, status=1, ipAttribution=)]
    2018-05-05 xlysu
  9. 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