Lancet Oncol:结肠癌全结肠系膜切除术可获更高无病生存率

2015-01-04 Hakim Lee MedSci原创

通过全结肠系膜切除术(CME)应用结肠癌全直肠系膜切除(TME)的原则被认为可改善肿瘤患者的预后。近日,丹麦Hillerød大学医院、哥本哈根大学等处丹麦结直肠癌协作组(DCCG)的学者进行了一项以人群为基础的回顾性研究,发现结肠癌患者行全结肠系膜切除术(CME)较传统结肠癌切除可获得更高的无病生存率,最新研究成果在线发表于12月30日的The Lancet Oncology杂志上。

通过全结肠系膜切除术(CME)应用结肠癌全直肠系膜切除(TME)的原则被认为可改善肿瘤患者的预后。 近日,丹麦Hillerød大学医院、哥本哈根大学等处丹麦结直肠癌协作组(DCCG)的学者进行了一项以人群为基础的回顾性研究,发现结肠癌患者行全结肠系膜切除术(CME)较传统结肠癌切除可获得更高的无病生存率,最新研究成果在线发表于12月30日的The Lancet Oncology杂志上。 该研究纳入丹麦首都地区2008-6-1至2011-12-31期间接受选择性切除术的国际抗癌联盟(UICC)I-III期结肠腺癌患者人群。全结肠系膜切除术组364例,传统切除对照组1031例。、 研究结果显示,全结肠系膜切除术组患者4年无病生存率为85.8%(95%CI 81.4-90.1),传统切除对照组为75.9%(72.2-79.7,log-rank p=0.0010)。UICC I期患者4年无病生存率在全结肠系膜切除术组为100%,传统对照组为89.8%(83.1-96.6,log-rank p=0.046);UICC II、III期患者此数据分别为91.9%(95%CI 87.2-96.

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    2015-11-23 howi
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    2015-03-05 lovetcm

    需要说哪一个分期获益更大

    0

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    2015-05-27 minlingfeng
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    2015-01-06 zzc2216