Anesthesiology:腰麻下左侧卧位行择期剖宫产术对新生儿酸碱状况无影响:一项随机对照试验

2017-11-17 雷涓 “罂粟花”微信号

目前对剖腹产妇的建议包括左侧倾斜15°使子宫移位,以防止压迫腹主动脉,尽管几乎从未达到这种倾斜度。我们假设,在当代临床实践中,包括维持基础收缩压的晶体灌注和去氧肾上腺素输注,接受择期剖宫产分娩的脊髓麻醉产妇中,母亲体位对新生儿酸碱状态的没有影响。

背景与目的:目前对剖腹产妇的建议包括左侧倾斜15°使子宫移位,以防止压迫腹主动脉,尽管几乎从未达到这种倾斜度。我们假设,在当代临床实践中,包括维持基础收缩压的晶体灌注和去氧肾上腺素输注,接受择期剖宫产分娩的脊髓麻醉产妇中,母亲体位对新生儿酸碱状态的没有影响。

方  法:择期剖宫产的健康妇女随机(非盲)分入脊髓麻醉(高比重布比卡因12 mg,芬太尼15μg,无防腐剂吗啡150μg)后仰卧水平(仰卧,n = 50)或手术台倾斜15°组(倾斜,n = 50)。鞘内注射后予乳酸林格氏液10?ml/kg 和去氧肾上腺素静脉滴注维持至100%基础收缩压。主要结局是脐动脉血碱剩余。

结  果:脐动脉血碱剩余或pH组间无差异。仰卧位组(n = 50)平均脐动脉血碱剩余(±SD)为-0.5 mM(±1.6),倾斜组为-0.6 mM(±1.5)(n = 47)(P = 0.64)。脊髓麻醉后15min内仰卧位组平均去氧肾上腺素需求量增大(P = 0.002),平均心输出量降低(P = 0.014)。

结  论:健康女性中,当母体收缩压以补液和去氧肾上腺素输注维持时,脊髓麻醉下择期剖宫产术后产妇仰卧位与左侧倾斜为15°相比不影响新生儿酸碱状态。这些发现可能不适用于紧急情况或不乐观的胎儿状态。

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    2018-08-01 amyloid
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    2017-11-19 skhzy
  7. [GetPortalCommentsPageByObjectIdResponse(id=1987196, encodeId=246a198e1962e, content=<a href='/topic/show?id=bac5466546c' target=_blank style='color:#2F92EE;'>#对照试验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46654, encryptionId=bac5466546c, topicName=对照试验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ad9f79, createdName=般若傻瓜, createdTime=Sun Apr 22 10:44:00 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775365, encodeId=9a3a1e75365a6, content=<a href='/topic/show?id=937d46650bf' target=_blank style='color:#2F92EE;'>#对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46650, encryptionId=937d46650bf, topicName=对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8ae138776909, createdName=amyloid, createdTime=Wed Aug 01 14:44:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050943, encodeId=49c320509432a, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Sep 21 01:44:00 CST 2018, time=2018-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296182, encodeId=da16129618250, content=<a href='/topic/show?id=7591984530b' target=_blank style='color:#2F92EE;'>#随机对照试验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98453, encryptionId=7591984530b, topicName=随机对照试验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373b263, createdName=lisa438, createdTime=Sun Nov 19 03:44:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546140, encodeId=68381546140fd, content=<a href='/topic/show?id=44b18551213' target=_blank style='color:#2F92EE;'>#腰麻#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85512, encryptionId=44b18551213, topicName=腰麻)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d2713885750, createdName=ms1774076774505970, createdTime=Sun Nov 19 03:44:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588281, encodeId=39b71588281cb, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Sun Nov 19 03:44:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=262028, encodeId=e6e3262028d8, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Fri Nov 17 13:26:36 CST 2017, time=2017-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=262023, encodeId=dbfb262023a4, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Fri Nov 17 13:17:44 CST 2017, time=2017-11-17, status=1, ipAttribution=)]
    2017-11-17 惠映实验室

    学习了.谢谢.

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1987196, encodeId=246a198e1962e, content=<a href='/topic/show?id=bac5466546c' target=_blank style='color:#2F92EE;'>#对照试验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46654, encryptionId=bac5466546c, topicName=对照试验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ad9f79, createdName=般若傻瓜, createdTime=Sun Apr 22 10:44:00 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775365, encodeId=9a3a1e75365a6, content=<a href='/topic/show?id=937d46650bf' target=_blank style='color:#2F92EE;'>#对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46650, encryptionId=937d46650bf, topicName=对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8ae138776909, createdName=amyloid, createdTime=Wed Aug 01 14:44:00 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050943, encodeId=49c320509432a, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Sep 21 01:44:00 CST 2018, time=2018-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296182, encodeId=da16129618250, content=<a href='/topic/show?id=7591984530b' target=_blank style='color:#2F92EE;'>#随机对照试验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98453, encryptionId=7591984530b, topicName=随机对照试验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373b263, createdName=lisa438, createdTime=Sun Nov 19 03:44:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546140, encodeId=68381546140fd, content=<a href='/topic/show?id=44b18551213' target=_blank style='color:#2F92EE;'>#腰麻#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85512, encryptionId=44b18551213, topicName=腰麻)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d2713885750, createdName=ms1774076774505970, createdTime=Sun Nov 19 03:44:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588281, encodeId=39b71588281cb, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Sun Nov 19 03:44:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=262028, encodeId=e6e3262028d8, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Fri Nov 17 13:26:36 CST 2017, time=2017-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=262023, encodeId=dbfb262023a4, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Fri Nov 17 13:17:44 CST 2017, time=2017-11-17, status=1, ipAttribution=)]
    2017-11-17 183****7028

    学习

    0

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