JAMA Surg:连续性肾脏替代治疗会增加外科ICU患者的死亡风险

2017-06-26 zhangfan MedSci原创

连续性肾脏替代治疗是许多重症患者必要的生命维持手段,但CRRT期间外科ICU患者的死亡率显著增加,特别是肝移植等待期患者

对于血流动力学不稳定的间歇性血液透析肾衰竭患者,治疗期的连续性肾脏替代治疗(CRRT)往往收益较大,但持续治疗效果较差。目前CRRT疗法对于急重症患者的效果尚不清楚。近日研究人员评估了影响外科ICU患者使用CRRT的独立危险因素以及生存率。

研究人员对于2012-2016年间,进行CRRT治疗的ICU患者进行顾性队列研究,患者包括手术前后的一般手术或肝移植前患者。主要终点是ICU患者进行连续肾脏替代治疗后的住院死亡率。

研究共包含108名患者,其中59.3%为男性,平均年龄62岁,其中53人为一般手术患者,55人为移植手术前患者。其中22名移植前患者在接受7天以上的CRRT后有13人死亡(59.1%);而12名一般手术患者在接受7天以上的CRRT后全部死亡。在一般手术组,CRRT每延长一天患者死亡风险的比值比增加1.39 (95% CI,1.01-1.90; P=0.04)。

连续性肾脏替代治疗是许多重症患者必要的生命维持手段,但CRRT期间外科ICU患者的死亡率显著增加,特别是肝移植等待期患者。

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    2017-06-26 Y—xianghai

    学习了新知识

    0

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    2017-06-26 执着追梦

    学习,感谢分享

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1692845, encodeId=af0a169284575, content=<a href='/topic/show?id=e6d86032ee8' target=_blank style='color:#2F92EE;'>#替代治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60327, encryptionId=e6d86032ee8, topicName=替代治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b79d29305168, createdName=wfang555, createdTime=Fri Nov 24 03:11:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2019882, encodeId=ab5b201988241, content=<a href='/topic/show?id=e1e4945558d' target=_blank style='color:#2F92EE;'>#连续性肾脏替代治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94555, encryptionId=e1e4945558d, topicName=连续性肾脏替代治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIuNQXObUwZmFG3VcZa2uhFq27sY7vfTowUhQCgRj2bj1odUibMF4sFXpuRLf6IE5t5yGVDSiaOoOcQ/132, createdBy=1e622500088, createdName=ms1065684921169360, createdTime=Fri Apr 27 01:11:00 CST 2018, time=2018-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255649, encodeId=8c401255649c0, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Jun 28 00:11:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394741, encodeId=70cf1394e413a, content=<a href='/topic/show?id=e31982e0603' target=_blank style='color:#2F92EE;'>#肾脏替代治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82706, encryptionId=e31982e0603, topicName=肾脏替代治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7482500171, createdName=ms4468361851264128, createdTime=Wed Jun 28 00:11:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595352, encodeId=cc851595352b7, content=<a href='/topic/show?id=44b993e977' target=_blank style='color:#2F92EE;'>#ICU患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9379, encryptionId=44b993e977, topicName=ICU患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=003c18235152, createdName=piaojinhua, createdTime=Wed Jun 28 00:11:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215557, encodeId=0d9c21555eae, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Jun 26 09:33:41 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215548, encodeId=de3c215548d7, content=学习,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Mon Jun 26 09:24:17 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215543, encodeId=4ecf215543f4, content=路过。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLEjPHcBWkEawnOHuvuXw3Lxjnzko8jRkakGyVZ27zRcmYACibkCom9Da1icAJBDFrbJelRNtMRic3H3/0, createdBy=152c1940043, createdName=Lke, createdTime=Mon Jun 26 09:15:34 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
    2017-06-26 Lke

    路过。。。。。。。。

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