WCC 2014：射血分数减少的慢性心衰患者临床特征和长期预后

2014-05-07 cath 编译医学论坛网

中国医学科学院阜外心血管病医院的学者们探讨了中国射血分数减少型慢性心衰(CHF—REF)患者的当前治疗状态，评估了此类患者的长期生存情况，分析其全因死亡和心脏性猝死(SCD)的独立预测因素。结果表明，尽管中国CHF—REF患者(尤其是扩张型心肌病患者)经过了当前的标准治疗，但其预后仍然较差。应辨别CHF—REF患者全因死亡和SCD的预测因素，以更好的评估这些患者的预后。该研究纳入10所医院的2

中国医学科学院阜外心血管病医院的学者们探讨了中国射血分数减少型慢性心衰(CHF—REF)患者的当前治疗状态，评估了此类患者的长期生存情况，分析其全因死亡和心脏性猝死(SCD)的独立预测因素。结果表明，尽管中国CHF—REF患者(尤其是扩张型心肌病患者)经过了当前的标准治疗，但其预后仍然较差。应辨别CHF—REF患者全因死亡和SCD的预测因素，以更好的评估这些患者的预后。

该研究纳入10所医院的2368例CHF—REF患者，其中2154例患者有完整的随访数据。对两种病原学亚组[扩张型心肌病(DCM)和缺血性心肌病(ICM)]进行了分类。分析患者的临床数据和长期预后情况。

结果显示，在中期随访52个月后，850例(39.46%)患者死亡，这其中302例(35.53%)发生了SCD。与ICM患者相比，DCM患者的全因死亡和SCD未校正发生率较高，但在校正联合变量后两亚组的死亡率相似。

以血管紧张素转换酶抑制剂(ACEI)/血管紧张素受体拮抗剂(ARB)、醛固酮受体拮抗剂、β受体阻滞剂和利尿剂为主导处方药的比率分别为65.97%、74.61%、 68.29%和74.37%。

多变量分析显示，NYHA分级、室性心动过速/室颤(VT/VF)、QRS间期、左心室射血分数(LVEF)和血肌酐为死亡的独立预测因素，而ACEI/ ARB、β受体阻滞剂和他汀类药物与预后较佳具有相关性。VT/VF持续发作对SCD的预测价值最高(HR 4.230，P<0.001)。DCM和 ICM患者死亡的预测因子不同。

文章译自本届世界心脏病学大会(WCC2014)的口头报告摘要，摘要号为0049。

口头报告摘要标题：Clinical characteristics and long-term prognosis in patients with chronic heart failure and reduced ejection fraction in China

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2015-03-05 happypig

可以啊，多学习

110 0
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2014-07-29 yeye5224612

#临床特征#

28 0
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2014-10-06 ymljack

#长期预后#

21 0
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2014-07-10 ms3153534357578991

#WCC#

38 0
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2014-05-16 habb

#射血分数减少#

35 0
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2014-06-29 lidage

射血分数减少的慢性心衰5年死亡率相当于癌症

106 0
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2014-06-09 115.238.243.65

射血分数减少的慢性心衰患者临床特征和长期预后

125 0
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2014-05-09 yuanming7

#心衰患者#

21 0

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WCC 2014：射血分数减少的慢性心衰患者临床特征和长期预后

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