FASEB J:产妇摄入高胆碱食物或会减少婴儿高血压和糖尿病的风险

2012-09-03 丁香园 丁香园

来自于美国康奈尔大学的研究显示,产妇在孕晚期增加胆碱摄入可能会减少婴儿今后发生与代谢和长期应激相关的高血压和糖尿病的风险。研究结果发布在最新一期的美国社团联合会杂志实验生物学上,文章指出,在鸡蛋等食物中含量很高的胆碱可以帮助婴儿对抗母亲怀孕期间的应激影响。以往的研究指出,如果在怀孕期间如果由于对于即将成为母亲这件事情产生较多的焦虑或者抑郁情绪导致接受较多的应激激素皮质醇的刺激,可能会导致其婴儿对于

来自于美国康奈尔大学的研究显示,产妇在孕晚期增加胆碱摄入可能会减少婴儿今后发生与代谢和长期应激相关的高血压糖尿病的风险。研究结果发布在最新一期的美国社团联合会杂志实验生物学上,文章指出,在鸡蛋等食物中含量很高的胆碱可以帮助婴儿对抗母亲怀孕期间的应激影响。以往的研究指出,如果在怀孕期间如果由于对于即将成为母亲这件事情产生较多的焦虑或者抑郁情绪导致接受较多的应激激素皮质醇的刺激,可能会导致其婴儿对于应激情况下诱导的疾和慢性病的抵抗力下降。这一研究又为胆碱在胎儿期的重要作用提供了重要证据。

研究详情

24名孕后期(妊娠最后3个月)的女性随机分组,分别给与为期12周的每天480mg胆碱和930mg的胆碱。研究人员收集了进入研究的24名母亲的血液样本,与胎盘的血液样本以及胎盘的组织样本。接着研究人员对比了这些样本的皮质醇水平与基因差异。研究人员发现,胎盘中皮质醇水平较低,并且在摄入高水平的胆碱组受试产妇中,调控皮质醇的基因在胎盘和婴儿组织中都发生了改变。康奈尔大学的医学博士同时也是这项研究的主要负责人Marie Caudill 称,“这项研究发现,产妇较高的胆碱摄入产生的较高的兴奋性可以对抗怀孕对于行为,神经内分泌,以及新陈代谢造成的不良影响

胆碱:一个至关重要的营养物

胆碱对于产妇至关重要,研究显示胆碱在胎儿与婴儿的脑发育过程中起到非常重要的作用,它影响大脑对于记忆以及终身学习的反应性。此外,研究显示,饮食中胆碱摄入较少的女性发生神经管缺陷,像是脊柱裂的危险性增加4倍。

研究还显示胆碱在其他方向可能还有其他额外的好处,包括:

预防乳腺癌:国家健康研究院投资的研究发现,饮食中胆碱的摄入可以减少大约24%的乳腺癌的发生危险。

对抗炎症:富含胆碱的食物可以减少与慢性疾病像是心血管疾病,骨质疏松,痴呆以及阿尔茨海默氏病的风险。

大脑功能:胆碱可以通过保护脑细胞膜的结构来增强成年人的大脑功能,同样胆碱也是乙酰胆碱的重要组成成分,而乙酰胆碱是参与记忆与肌肉控制的重要神经递质。

胆碱的好来源

尽管胆碱对于身体至关重要,但是平均10个美国人中只有1人符合指南中胆碱的足量摄入。鸡蛋是胆碱的绝好来源,每个鸡蛋包含125mg的胆碱。注册营养师兼营养交流顾问Neva Cochran,解释称,鸡蛋的营养益处远远不限于胆碱。“鸡蛋不仅是胆碱的绝好来源,鸡蛋中还含有产妇必须的营养物质,像是高质量的蛋白,铁离子以及叶酸。为了可以摄取到足够量的胆碱,Cochran提出了如下建议:

在食物中寻找;日常胆碱摄入的好方法就是摄入富含胆碱的食物,像是鸡蛋,瘦牛肉,花椰菜和花生。同时记住大部分维生素,甚至是产前服用的维生素,所提供的胆碱的摄入量都远远不够。

不要不吃蛋黄:胆碱专门存在于鸡蛋的蛋黄中,而不是蛋清中。蛋黄中还包含至少一半的蛋白与大部分的维生素和矿物质。

链接;

Jiang X, Yan J, West AA, Perry CA, Malysheva OV, Devapatla S, Pressman E, Vermeylen F, Caudill MA.Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans.FASEB J. 2012 Aug;26(8):3563-74

 

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2057881, encodeId=f119205e881b0, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Thu Feb 28 17:19:00 CST 2013, time=2013-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822332, encodeId=6039182233203, content=<a href='/topic/show?id=4e6b102605d7' target=_blank style='color:#2F92EE;'>#高胆碱食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102605, encryptionId=4e6b102605d7, topicName=高胆碱食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Feb 11 21:19:00 CST 2013, time=2013-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416633, encodeId=a7ae14166332a, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527367, encodeId=8628152e3679a, content=<a href='/topic/show?id=10b483495a2' target=_blank style='color:#2F92EE;'>#胆碱#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83495, encryptionId=10b483495a2, topicName=胆碱)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce6211859522, createdName=grace5704, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=)]
    2013-02-28 gracezdd
  2. [GetPortalCommentsPageByObjectIdResponse(id=2057881, encodeId=f119205e881b0, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Thu Feb 28 17:19:00 CST 2013, time=2013-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822332, encodeId=6039182233203, content=<a href='/topic/show?id=4e6b102605d7' target=_blank style='color:#2F92EE;'>#高胆碱食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102605, encryptionId=4e6b102605d7, topicName=高胆碱食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Feb 11 21:19:00 CST 2013, time=2013-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416633, encodeId=a7ae14166332a, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527367, encodeId=8628152e3679a, content=<a href='/topic/show?id=10b483495a2' target=_blank style='color:#2F92EE;'>#胆碱#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83495, encryptionId=10b483495a2, topicName=胆碱)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce6211859522, createdName=grace5704, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2057881, encodeId=f119205e881b0, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Thu Feb 28 17:19:00 CST 2013, time=2013-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822332, encodeId=6039182233203, content=<a href='/topic/show?id=4e6b102605d7' target=_blank style='color:#2F92EE;'>#高胆碱食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102605, encryptionId=4e6b102605d7, topicName=高胆碱食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Feb 11 21:19:00 CST 2013, time=2013-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416633, encodeId=a7ae14166332a, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527367, encodeId=8628152e3679a, content=<a href='/topic/show?id=10b483495a2' target=_blank style='color:#2F92EE;'>#胆碱#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83495, encryptionId=10b483495a2, topicName=胆碱)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce6211859522, createdName=grace5704, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=)]
    2012-09-05 yhy100201
  4. [GetPortalCommentsPageByObjectIdResponse(id=2057881, encodeId=f119205e881b0, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Thu Feb 28 17:19:00 CST 2013, time=2013-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822332, encodeId=6039182233203, content=<a href='/topic/show?id=4e6b102605d7' target=_blank style='color:#2F92EE;'>#高胆碱食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102605, encryptionId=4e6b102605d7, topicName=高胆碱食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Feb 11 21:19:00 CST 2013, time=2013-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416633, encodeId=a7ae14166332a, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527367, encodeId=8628152e3679a, content=<a href='/topic/show?id=10b483495a2' target=_blank style='color:#2F92EE;'>#胆碱#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83495, encryptionId=10b483495a2, topicName=胆碱)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce6211859522, createdName=grace5704, createdTime=Wed Sep 05 07:19:00 CST 2012, time=2012-09-05, status=1, ipAttribution=)]
    2012-09-05 grace5704