Heart:减肥手术可降低稳定型心绞痛患者住院率!!!

2017-02-17 xing.T MedSci原创

由此可见,在以人群为基础的肥胖成年SAP患者研究中,患者因SAP的住院率在减肥手术后降低了三分之二。

肥胖与稳定型心绞痛(SAP)是美国重要的公共卫生问题,然而,关于减肥是否会影响SAP相关的发病率仍然知之甚少。近日,在心脏病领域权威杂志Heart上发表了一篇荟萃分析文章,研究人员旨在检验减肥手术可以降低肥胖成年SAP患者的住院率这一假设。

研究人员在2005年至2011年期间采用美国3个州(加利福尼亚、佛罗里达和内布拉斯加)的人群为基础的住院病人数据库,在接受减肥手术的肥胖成年SAP患者进行了一项自身对照病例系列研究。该研究的主要终点是因SAP的住院治疗情况。研究人员采用条件Logistic回归分析比较了连续12个月期间研究结局事件的发生率,采用术前13-24个月作为对照期。

该研究的样本包括了953例接受减肥手术的SAP患者。其年龄中位数为57岁,女性占51%,非西班牙裔白人占78%。在对照期,25.3%(95%可信区间为22.5%-28.1%)患者因SAP而住院治疗。在随后的术前12个月患者因SAP的住院率保持稳定(调整的比值比为0.84(95%可信区间为0.69-1.02);P=0.07)。在减重手术后的前12个月期间,研究人员观察到患者因SAP的住院率发生显著降低(9.1%(95%可信区间为7.3%-11%);调整的比值比为0.33(95%可信区间为0.26-0.43);P<0.0001)。同样地,在减肥手术后随后的13-24个月,患者因SAP的住院率仍然显著降低(8.7%(95% 可信区间为6.9%-10.5%);调整的比值比为0.31(95%可信区间为0.24-0.41);P<0.0001)。

由此可见,在以人群为基础的肥胖成年SAP患者研究中,患者因SAP的住院率在减肥手术后降低了三分之二。

原始出处:


Yuichi J Shimada,et al. Association between bariatric surgery and rate of hospitalisations for stable angina pectoris in obese adults. Heart. 2017. http://heart.bmj.com/content/early/2017/02/11/heartjnl-2016-310757

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    2017-02-21 1771ae4158m

    学习一下很不错

    0

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    2017-02-19 zhaojie88
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    2017-02-19 slcumt
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    2017-02-18 Anima

    稳定型心绞痛

    0

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