Crit Care:围手术期目标导向血流动力学治疗对腹部手术后益处多多!

2017-06-17 MedSci MedSci原创

目标定向的血液动力学治疗(GDHT)多年来一直用于临床。然而,GDHT对术后恢复有益的证据仍然不一致。近期,一项发表在Crit Care上的研究系统评价和荟萃分析了与常规液体治疗相比,围手术期GDHT对大型腹部手术患者术后恢复的影响。此项研究为随机对照试验(RCT),研究者们评估并比较了与采用常规流体疗法的成人腹部手术(即> 16年)相比,围手术期使用GDHT对术后恢复的影响。计算95%CI

目标定向的血液动力学治疗(GDHT)多年来一直用于临床。然而,GDHT对术后恢复有益的证据仍然不一致。近期,一项发表在Crit Care上的研究系统评价和荟萃分析了与常规液体治疗相比,围手术期GDHT对大型腹部手术患者术后恢复的影响。


此项研究为随机对照试验(RCT),研究者们评估并比较了与采用常规流体疗法的成人腹部手术(即> 16年)相比,围手术期使用GDHT对术后恢复的影响。计算95%CI的效应大小。

此项研究共纳入了45个符合条件的RCT。围手术期的GDHT与短期死亡率(风险比[RR] 0.75,95%CI 0.61-0.91,p = 0.004,I2 = 0),长期死亡率(RR 0.80,95%CI 0.64 -0.99,p = 0.04,I2 = 4%)和总体并发症发生率(RR 0.76,95%CI 0.68-0.85,p <0.0001,I2 = 38%)的明显降低相关。 GDHT也可以促进胃肠功能恢复,如可以缩短首次通气时间0.4天(95%CI -0.72至-0.08,p = 0.01,I 2 = 74%)和口服饮食耐受时间0.74天(95%CI -1.44〜-0.03,p <0.0001,I2 = 92%)。

此项系统评估表明,围手术期GDHT的使用可以促进经历重大腹部手术的患者的恢复。

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    2017-06-18 明天会更好!

    感谢分享!继续关注!

    0

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    2017-06-17 虈亣靌

    不错的,学习了,谢谢分享!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1812038, encodeId=0404181203824, content=<a href='/topic/show?id=d7a1891613d' target=_blank style='color:#2F92EE;'>#血流动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89161, encryptionId=d7a1891613d, topicName=血流动力)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Mar 15 10:02:00 CST 2018, time=2018-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756480, encodeId=7ae01e56480d3, content=<a href='/topic/show?id=3bf48568e5e' target=_blank style='color:#2F92EE;'>#腹部手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85687, encryptionId=3bf48568e5e, topicName=腹部手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=871937156800, createdName=ms622625817193301, createdTime=Mon Sep 18 01:02:00 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2053774, encodeId=97a12053e7449, content=<a href='/topic/show?id=8f5a54442a1' target=_blank style='color:#2F92EE;'>#手术期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54442, encryptionId=8f5a54442a1, topicName=手术期)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/WQ1WyMBGic8d2fKdCe6Cm3vaRh4X8YnlumYndC46iagNCBl9Df8RtoCaQchnFtZldHUctGJjsgsyutUlu8vPq6yQ/132, createdBy=97862500016, createdName=ms3117646317107274, createdTime=Thu Mar 29 21:02:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391988, encodeId=256f1391988cd, content=<a href='/topic/show?id=3704891621c' target=_blank style='color:#2F92EE;'>#血流动力学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89162, encryptionId=3704891621c, topicName=血流动力学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99cf2500102, createdName=zjshifan_98647306, createdTime=Mon Jun 19 07:02:00 CST 2017, time=2017-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212067, encodeId=b49b21206e5c, content=感谢分享!继续关注!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sun Jun 18 00:15:47 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212014, encodeId=b67b21201475, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Jun 17 20:29:45 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212003, encodeId=756221200311, content=学习了,受益匪浅。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Jun 17 19:49:10 CST 2017, time=2017-06-17, status=1, ipAttribution=)]
    2017-06-17 131****1460

    学习了,受益匪浅。

    0