Stroke: 短暂性脑缺血发作的流行病学调查

2017-04-22 MedSci MedSci原创

背景:最近几年短暂性脑缺血发作(TIA)流行病学可能发生了变化,对血管危险因素的识别和治疗得到改善。研究者旨在提供意大利TIA流行病学的最新信息。方法: 在基于人群的前瞻性登记记录中,识别2011年1月1日到2012年12月31日首发短暂性脑缺血发作的患者。拉奎拉地区所有居民TIA后,纳入研究并对其随访2年。结果事件包括TIA再发、非致死性和致死性卒中、非致死性和致死性心肌梗死和全因死亡率。结果:

背景:最近几年短暂性脑缺血发作(TIA)流行病学可能发生了变化,对血管危险因素的识别和治疗得到改善。研究者旨在提供意大利TIA流行病学的最新信息。

方法: 在基于人群的前瞻性登记记录中,识别2011年1月1日到2012年12月31日首发短暂性脑缺血发作的患者。拉奎拉地区所有居民TIA后,纳入研究并对其随访2年。结果事件包括TIA再发、非致死性和致死性卒中、非致死性和致死性心肌梗死和全因死亡率。

结果:按照传统的基于时间的定义共有210例TIA患者(51.4%为女性);基于组织定义的TIA患者151例(71.9%),即存在短暂的症状和阴性的脑神经影像,29例患者(13.8%)出现短暂的症状且存在急性缺血性病变,30例(14.3%)有急性血管综合征。传统的基于时间的TIA年发病率为35.2/100 000(95%CI,30.6-40.3),与2011的欧洲人口标准化后,年发病率为28.6/100 000(95%CI,24.1-33.5)。超过85岁的男性和女性患者,TIA的发生达到高峰。在随访的2年中,结果事件发生50例(23.8%),包括15例(7.1%)非致命性或致命性卒中患者。

结论:基于人口的研究发现,TIA年发生率降低,TIA预后证实心血管疾病预防策略的有效性。研究者也证明基于组织定义TIA的不适用性。

原文出处:

Degan D, Ornello R, et al. Epidemiology of Transient Ischemic Attacks Using Time- or Tissue-Based Definitions: A Population-Based Study. Stroke. 2017 Mar.


本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1764504, encodeId=25b01e6450470, content=<a href='/topic/show?id=1612e319263' target=_blank style='color:#2F92EE;'>#短暂性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73192, encryptionId=1612e319263, topicName=短暂性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b6237741961, createdName=12498ca5m95暂无昵称, createdTime=Thu May 11 17:02:00 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1800812, encodeId=f2a71800812c2, content=<a href='/topic/show?id=8a3be319614' target=_blank style='color:#2F92EE;'>#短暂性脑缺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73196, encryptionId=8a3be319614, topicName=短暂性脑缺)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Oct 05 19:02:00 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289193, encodeId=8207128919300, content=<a href='/topic/show?id=cd268500578' target=_blank style='color:#2F92EE;'>#脑缺血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85005, encryptionId=cd268500578, topicName=脑缺血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411258, encodeId=99b21411258ce, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423786, encodeId=4f941423e8677, content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1764504, encodeId=25b01e6450470, content=<a href='/topic/show?id=1612e319263' target=_blank style='color:#2F92EE;'>#短暂性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73192, encryptionId=1612e319263, topicName=短暂性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b6237741961, createdName=12498ca5m95暂无昵称, createdTime=Thu May 11 17:02:00 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1800812, encodeId=f2a71800812c2, content=<a href='/topic/show?id=8a3be319614' target=_blank style='color:#2F92EE;'>#短暂性脑缺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73196, encryptionId=8a3be319614, topicName=短暂性脑缺)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Oct 05 19:02:00 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289193, encodeId=8207128919300, content=<a href='/topic/show?id=cd268500578' target=_blank style='color:#2F92EE;'>#脑缺血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85005, encryptionId=cd268500578, topicName=脑缺血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411258, encodeId=99b21411258ce, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423786, encodeId=4f941423e8677, content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1764504, encodeId=25b01e6450470, content=<a href='/topic/show?id=1612e319263' target=_blank style='color:#2F92EE;'>#短暂性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73192, encryptionId=1612e319263, topicName=短暂性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b6237741961, createdName=12498ca5m95暂无昵称, createdTime=Thu May 11 17:02:00 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1800812, encodeId=f2a71800812c2, content=<a href='/topic/show?id=8a3be319614' target=_blank style='color:#2F92EE;'>#短暂性脑缺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73196, encryptionId=8a3be319614, topicName=短暂性脑缺)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Oct 05 19:02:00 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289193, encodeId=8207128919300, content=<a href='/topic/show?id=cd268500578' target=_blank style='color:#2F92EE;'>#脑缺血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85005, encryptionId=cd268500578, topicName=脑缺血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411258, encodeId=99b21411258ce, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423786, encodeId=4f941423e8677, content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1764504, encodeId=25b01e6450470, content=<a href='/topic/show?id=1612e319263' target=_blank style='color:#2F92EE;'>#短暂性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73192, encryptionId=1612e319263, topicName=短暂性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b6237741961, createdName=12498ca5m95暂无昵称, createdTime=Thu May 11 17:02:00 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1800812, encodeId=f2a71800812c2, content=<a href='/topic/show?id=8a3be319614' target=_blank style='color:#2F92EE;'>#短暂性脑缺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73196, encryptionId=8a3be319614, topicName=短暂性脑缺)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Oct 05 19:02:00 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289193, encodeId=8207128919300, content=<a href='/topic/show?id=cd268500578' target=_blank style='color:#2F92EE;'>#脑缺血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85005, encryptionId=cd268500578, topicName=脑缺血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411258, encodeId=99b21411258ce, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423786, encodeId=4f941423e8677, content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=)]
    2017-04-24 xugumin
  5. [GetPortalCommentsPageByObjectIdResponse(id=1764504, encodeId=25b01e6450470, content=<a href='/topic/show?id=1612e319263' target=_blank style='color:#2F92EE;'>#短暂性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73192, encryptionId=1612e319263, topicName=短暂性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b6237741961, createdName=12498ca5m95暂无昵称, createdTime=Thu May 11 17:02:00 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1800812, encodeId=f2a71800812c2, content=<a href='/topic/show?id=8a3be319614' target=_blank style='color:#2F92EE;'>#短暂性脑缺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73196, encryptionId=8a3be319614, topicName=短暂性脑缺)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Oct 05 19:02:00 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289193, encodeId=8207128919300, content=<a href='/topic/show?id=cd268500578' target=_blank style='color:#2F92EE;'>#脑缺血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85005, encryptionId=cd268500578, topicName=脑缺血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411258, encodeId=99b21411258ce, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423786, encodeId=4f941423e8677, content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Mon Apr 24 00:02:00 CST 2017, time=2017-04-24, status=1, ipAttribution=)]

相关资讯

Plos Med:卒中和短暂性脑缺血发作一级预防药物治疗需要加大处方力度!

超过一半的人适合降脂、抗凝或抗高血压药物治疗,但在发生第一次卒中和短暂性脑缺血发作之前在处方中都没有写明需要服用这些药物。研究人员估计,如果通过将这些药物最佳时机写入处方,在英国每年约有12000次卒中事件可能会被预防。提高降脂、抗凝和抗高血压药物写入处方的比例是降低卒中和短暂性脑缺血发作发病率和负担的重要措施。

Stroke:收缩压与血管性痴呆的风险呈正相关

背景:血管性痴呆是第二大常见痴呆形式,但血压(BP)和血管性痴呆发生的风险特定年龄的相关性的可靠证据是有限的,一些研究报告在年龄较大的负面联想。方法:从电子初级保健健康档案(英国临床实践研究数据库)中识别无已知的心血管疾病和老年痴呆症428万人。研究者将BP和诊断血管性痴呆的时间联系起来。研究者在短暂性脑缺血发作和卒中(牛津血管研究)中进行潜在性的记录,探讨血压和老年痴呆症之间的关联。结果:随访时

Stroke:缺血性卒中或短暂性脑缺血发作患者发生脑微梗死危险因素有哪些?

最近有研究表明,脑微梗死(CMIs)可在体内使用3.0特斯拉(T)磁共振成像检测。研究人员调查了在缺血性卒中或短暂性脑缺血发作患者中,使用3.0T磁共振成像检测的大脑皮层CMIs的患病率,危险因素,和纵向认知结果。 该研究共包括231例接受3.0T磁共振成像的患者。蒙特利尔认知评估被用来评估总体认知功能和认知域(记忆,语言和注意视觉空间和执行功能)。蒙特利尔认知评分评估了基线和卒中/短暂

2016中国短暂性脑缺血发作早期诊治指导规范发作

短暂性脑缺血发作(Transient ischemic attack,TIA)是脑、脊髓或视网膜局灶性缺血所致的、未发生急性脑梗死的短暂性神经功能障碍,TIA与缺血性卒中有着密不可分的联系,大量研究显示,TIA患者在近期有很高的卒中发生风险。相关荟萃分析指出,TIA患者发病后第2天、第7天、第30天和第90天内的卒中复发风险分别为3.5%、5.2%、8.0%和9.2%,上述数据证实TIA是急性缺血

Stroke:缺血性卒中和短暂性脑缺血发作患者有很高的房颤风险

与缺血性卒中(IS)相比,房颤(AF)与短暂性脑缺血发作(TIA)之间的联系还没有被建立。该研究的目的是评估与IS患者相比,TIA患者发生房颤的比例,这些患者的特点,以及和二级预防治疗。 来自瑞典的研究人员分析了从2011年7月至2013年6月期间登记的TIA和IS事件基于医院的数据,这些数据从瑞典卒中注册(Riksstroke)获得。该研究也应用了基于时间的TIA定义(症状的持续时间&

TIA后立即服这种药,卒中风险减少80% !

5月18日,《柳叶刀》杂志发表了一项由英国牛津大学开展的研究结果:在短暂性脑缺血发作(TIA)以及轻型卒中(minor stroke)发生后即刻给予阿司匹林,可降低数天或数周内致死致残性卒中70%~80%的发生风险。这一结果对临床医生有非常重要的指导意义。如果怀疑患者为TIA或小卒中,医生应立即给予其阿司匹林,而不是等待专科医生评估和检查。一、什么是TIA?小卒中?短暂性脑缺血发作简称TIA,是指