Ann Otol Rhinol Laryngol:孕期过敏性鼻炎是否影响产后抑郁风险?

2021-12-10 AlexYang MedSci原创

调查了怀孕期间过敏性鼻炎对产后抑郁症(PPD)发展的可能影响。

过敏性鼻炎(AR)是一种常见的疾病,能影响人的一生。据估计,全球约有10%至40%的人患有AR,其中包括了美国的约6000万人。诊断标准不一以及AR的错误治疗,给患者带来了巨大的直接和间接成本。虽然AR本身不是一种严重的疾病,但它却是许多其他并发症的基础,也是哮喘控制不佳的主要风险因素,影响生活质量以及工作或学习的效率

在普通人群中,过敏性鼻炎(AR)与重度抑郁症风险的增加有关,然而,既往研究没有评估过其在孕妇中产生的影响。近期,来自宁夏医科大学的研究人员在《Ann Otol Rhinol Laryngol》上发表文章,调查了怀孕期间过敏性鼻炎对产后抑郁症(PPD)发展的可能影响

研究为一项基于人群的病例对照研究。从国家健康保险研究数据库(NHIRD)中获取相关数据,纳入了2000年至2010年期间,总共199470例分娩的医疗记录。其中,1416名产后12个月内有PPD的女性列为病例组,198054名产后没有PPD的妇女列为对照组。单变量和多变量回归分析确定了怀孕期间的AR和其他研究变量与PPD之间的关联。

研究结果表明,发生PPD的女性中,怀孕期间存在AR的女性比例为9.53%,产后没有PPD的女性中,患AR的女性比例为5.44%。在多变量分析中,调整了分娩年龄、收入水平、各种与怀孕和分娩有关的情况、哮喘、特应性皮炎和其他医学合并症后,发现AR与PPD几率的增加显著相关(aOR:1.498,95%CI:1.222-1.836)。

研究变量和PPD之间的相关性情况

综上所述,怀孕期间的AR与产后女性PPD风险的增加有独立和显著的关系。因此,应密切监测AR,从而优化分娩后的母婴结果

原始出处:

Zhi-Chao Yang , Li-Xin Wang , Yang Yu et al. Increased Risk of Postpartum Depression in Women With Allergic Rhinitis During Pregnancy: A Population-Based Case-Control Study. Ann Otol Rhinol Laryngol. Nov 2021

 

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    2021-12-16 ms3000000920707852

    学习了

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    2021-12-11 ms5000000518166734

    学习已读已读已读已读已读已读已读你已读已读已读已读已读已读已读

    0

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