Stroke:大血管闭塞性卒中快速和缓慢进展的发病率和时间分布

2019-06-20 国际循环编辑部 国际循环

临床实践中,经常观察到由于前循环大血管闭塞引起的梗死快速和缓慢进展。近日,Stroke杂志发表一项研究,旨在评估卒中发病后24 h内诊断出的前循环大血管闭塞患者快速和缓慢进展者的发病率和时间分布。

临床实践中,经常观察到由于前循环大血管闭塞引起的梗死快速和缓慢进展。近日,Stroke杂志发表一项研究,旨在评估卒中发病后24 h内诊断出的前循环大血管闭塞患者快速和缓慢进展者的发病率和时间分布。

这项单中心回顾性研究,纳入85例前循环大血管闭塞患者,在卒中发病后24 h内接受基线计算机断层扫描灌注或磁共振成像。确定快速进展者(缺血核心> 70 ml,卒中发作<6 h)和缓慢进展者(缺血核心≤30 ml,卒中发作> 6~24 h)的患病率。

结果显示,从卒中发作到基线核心成像的中位时间间隔为7.6 h(四分位间距为3.9~13.2),中位核心体积为17 ml(范围0~405)。在整个队列中,72%的患者核心体积≤70 ml。快速进展者的患病率为25%(95%CI:17%~37%),并且在卒中发病后3~4.5 h内达到40%(95%CI:24%~59%)。缓慢进展者的患病率为55%(95%CI:46%~64%),并且在卒中发病后6 h内的时间间隔相似。

研究表明,大部分前循环大血管闭塞患者具有中小型缺血核心体积,无论卒中发作后24h内是否出现早期或延迟。快速进展者在卒中发病后3~4.5 h内非常普遍。

原始出处:
Marcelo Rocha Shashvat M. Desai,Ashutosh P. Jadhav,Tudor G. Jovin,et al.Prevalence and Temporal Distribution of Fast and Slow Progressors of Infarct Growth in Large Vessel Occlusion Stroke.Stroke,June 2019.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1815193, encodeId=49991815193e4, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Aug 08 18:44:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706141, encodeId=1bbf1e0614100, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Thu Jan 16 09:44:00 CST 2020, time=2020-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823565, encodeId=31b51823565f3, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Apr 06 00:44:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009854, encodeId=599a2009854fb, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Mon Feb 17 19:44:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026390, encodeId=98be102639081, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Jun 20 23:44:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1815193, encodeId=49991815193e4, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Aug 08 18:44:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706141, encodeId=1bbf1e0614100, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Thu Jan 16 09:44:00 CST 2020, time=2020-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823565, encodeId=31b51823565f3, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Apr 06 00:44:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009854, encodeId=599a2009854fb, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Mon Feb 17 19:44:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026390, encodeId=98be102639081, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Jun 20 23:44:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
    2020-01-16 kkunny
  3. [GetPortalCommentsPageByObjectIdResponse(id=1815193, encodeId=49991815193e4, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Aug 08 18:44:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706141, encodeId=1bbf1e0614100, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Thu Jan 16 09:44:00 CST 2020, time=2020-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823565, encodeId=31b51823565f3, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Apr 06 00:44:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009854, encodeId=599a2009854fb, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Mon Feb 17 19:44:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026390, encodeId=98be102639081, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Jun 20 23:44:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1815193, encodeId=49991815193e4, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Aug 08 18:44:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706141, encodeId=1bbf1e0614100, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Thu Jan 16 09:44:00 CST 2020, time=2020-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823565, encodeId=31b51823565f3, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Apr 06 00:44:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009854, encodeId=599a2009854fb, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Mon Feb 17 19:44:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026390, encodeId=98be102639081, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Jun 20 23:44:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1815193, encodeId=49991815193e4, content=<a href='/topic/show?id=5f519e1848c' target=_blank style='color:#2F92EE;'>#闭塞性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97184, encryptionId=5f519e1848c, topicName=闭塞性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Aug 08 18:44:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706141, encodeId=1bbf1e0614100, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Thu Jan 16 09:44:00 CST 2020, time=2020-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823565, encodeId=31b51823565f3, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Apr 06 00:44:00 CST 2020, time=2020-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009854, encodeId=599a2009854fb, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Mon Feb 17 19:44:00 CST 2020, time=2020-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026390, encodeId=98be102639081, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Jun 20 23:44:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
    2019-06-20 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

相关资讯

Stroke:洛杉矶运动量表(LAMS)对急性脑缺血的效用评估!

目前,因为大血管闭塞(LVO)可直接进入综合性中风中心(CSC),因此,已经开发了院前指数来识别急性脑缺血(ACI)患者,但很少有研究在院前环节进行验证,且其对颅内出血患者的作用尚未确定。近期,一项发表在杂志Stroke上的研究旨在验证洛杉矶运动量表(LAMS)对适合LVO和CSC患者(LVO ACI和颅内出血患者)的识别,并将LAMS与其他量表进行了比较。LAMS由救护人员对接受救护车前往医院的

Stroke:大血管闭塞患者:机械取栓前静脉溶栓SR情况如何?

2017年发表于《Stroke》上的一项系统评价和Meta分析,考察了大血管闭塞患者中,机械取栓前静脉溶栓(IVT)的成功再灌注(SR)情况。

Stroke:皮质症状可作为急性脑卒中患者大血管闭塞的院前指标

由此可见,研究人员建议在院前环境中,出现皮质症状可作为LVO的可靠指标,并且其存在证明了将患者转运至具有MT功能医疗中心是正确的。

急性大动脉闭塞患者机械取栓术后管理:美国神经介入外科学会指南

近年来,数项大型试验已证实急性大动脉闭塞( emergent large vessel occlusions,ELVOs) 所致的卒中患者能够从血管内治疗中获益。对ELVO 患者术前、术中和术后的管理问题备受关注。遗憾的是,目前很多与机械取栓相关卒中治疗的措施仍存在争议。本指南综合分析现有的最佳证据,以制定机械取栓术后患者管理的指导建议。

Stroke:入院中性粒细胞与淋巴细胞比率可作为大血管闭塞卒中结局的预后指标

由此可见,较高的入院NLR是机械性血栓切除术治疗的大血管闭塞患者症状性颅内出血和3个月死亡率的独立预测因子,其可以用于确定需要辅助抗炎治疗的目标人群。

Stroke:机械性血栓切除术治疗的大血管闭塞患者HbA1c与临床结局的关系

这些结果表明,在采用MT治疗的大血管闭塞患者中,较高HbA1c水平是AIS后3个月不良预后的独立预测因子,特别是在血管再通的患者中,并且可能增加AIS后死亡和早期临床恶化的风险。