J Periodontol:大麻的使用与牙周炎的发生相关

2018-03-11 MedSci MedSci原创

尽管数据有限,但研究表明大麻的使用与口腔HPV感染和牙周炎有关。本研究旨在波多黎各的西班牙裔成年人群中评估这些关联。 此横断面研究评估了735名成年人大麻的使用情况,通过音频计算机辅助自我访谈,以及根据国家健康和营养检查调查方法确定牙周炎,并收集口腔HPV样本。使用聚合酶链反应与修饰的L1共有引物(MY09/MY11)进行HPV分型。 结果显示,26.5%的成年人终身使用大麻,2.7%为频繁使用者

尽管数据有限,但研究表明大麻的使用与口腔HPV感染和牙周炎有关。本研究旨在波多黎各的西班牙裔成年人群中评估这些关联。

此横断面研究评估了735名成年人大麻的使用情况,通过音频计算机辅助自我访谈,以及根据国家健康和营养检查调查方法确定牙周炎,并收集口腔HPV样本。使用聚合酶链反应与修饰的L1共有引物(MY09/MY11)进行HPV分型。

结果显示,26.5%的成年人终身使用大麻,2.7%为频繁使用者(终身使用≥2次,过去一年使用≥6次,以及过去30天使用≥2次),5.7%为口HPV感染,20.1%有严重的牙周炎。多变量logistic回归分析显示,校正年龄、性别、医疗保险覆盖面、吸烟、暴饮酗酒、口交性伴数量和口腔HPV感染后,频繁使用大麻的患者较从未或仅使用一次的患者更有可能患有严重牙周炎(OR = 2.91,95%CI = 1.06-7.96)。然而,频繁使用大麻与口腔HPV感染无关。

综上所述,该研究结果表明,大麻的使用与牙周炎有关,但与口腔HPV感染无关。大麻使用者在口腔HPV感染和牙周炎中的作用的进一步评估可以为新型预防性公共健康策略提供信息,因为大麻使用者的口腔癌风险可能会增加。

原始出处:

Ortiz AP, González D, et al., Association of marijuana use with oral HPV infection and periodontitis among Hispanic adults: Implications for oral cancer prevention. J Periodontol. 2018 Feb 22. doi: 10.1002/JPER.17-0372.

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    2018-08-15 zhouqu_8
  2. [GetPortalCommentsPageByObjectIdResponse(id=1727143, encodeId=e0d71e2714369, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Aug 15 23:27:00 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272721, encodeId=ee4612e2721b2, content=<a href='/topic/show?id=d04f440581e' target=_blank style='color:#2F92EE;'>#大麻#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44058, encryptionId=d04f440581e, topicName=大麻)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87b1109, createdName=kcb069, createdTime=Tue Mar 13 07:27:00 CST 2018, time=2018-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450819, encodeId=d41c1450819d1, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Mar 13 07:27:00 CST 2018, time=2018-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295228, encodeId=333229522873, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Mar 11 19:22:32 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295209, encodeId=5775295209f5, content=好文章.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sun Mar 11 16:53:58 CST 2018, time=2018-03-11, status=1, ipAttribution=)]
    2018-03-13 kcb069
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    2018-03-11 天地飞扬

    了解一下.谢谢分享!

    0

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    2018-03-11 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0