Diabetes care:母亲妊娠期吸烟升高女儿患2型糖尿病风险

2014-08-06 CMT CMT糖尿病

一项美国和荷兰联合研究显示,整个生命过程中的体质指数(BMI)在很大程度上可解释妊娠期间母亲吸烟和父亲吸烟与女儿发生2型糖尿病风险的相关性。只在妊娠前三个月吸烟对后代胰岛素抵抗的影响仍须进一步研究来探索。论文8月4日在线发表于《糖尿病护理》(Diabetes Care) 杂志。 研究介绍 数据源于纳入了34453例受试者的护士健康研究Ⅱ,研究者应用了Cox比例风险模型评估了1989年~

一项美国和荷兰联合研究显示,整个生命过程中的体质指数(BMI)在很大程度上可解释妊娠期间母亲吸烟和父亲吸烟与女儿发生2型糖尿病风险的相关性。只在妊娠前三个月吸烟对后代胰岛素抵抗的影响仍须进一步研究来探索。论文8月4日在线发表于《糖尿病护理》(Diabetes Care) 杂志。

研究介绍

数据源于纳入了34453例受试者的护士健康研究Ⅱ,研究者应用了Cox比例风险模型评估了1989年~2009年父亲和母亲在妊娠期间吸烟与女儿2型糖尿病发生率的相关性。

研究结果

研究结果显示,母亲只在妊娠期前三个月吸烟与后代发生2型糖尿病的风险相关,与出生体重和日后BMI无关(完全校正风险比为1.34)。在年龄校正模型中,妊娠期间母亲持续吸烟和父亲吸烟与女儿发生2型糖尿病的风险升高有关。围产期和成年生活变量不能解释上述相关性,但进一步校正当前的BMI减弱了评估效果。

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    2015-04-11 x35042875

    糖尿病肾病进展风险的关系没有发现。

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    2014-08-16 智智灵药
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