Radiother Oncol:超脉冲CO2点阵激光联合30%超分子水杨酸能更好治疗痤疮疤痕

2022-09-11 MedSci原创 MedSci原创

多种方法被用于治疗痤疮疤痕,但有些方法价格昂贵、效果不佳,并会引起并发症。近日,一项研究评估了超脉冲二氧化碳点阵激光联合30%超分子水杨酸治疗痤疮疤痕的疗效和安全性。

痤疮是一种发生在青春期的毛囊和皮脂腺的慢性炎症性疾病。痤疮疤痕是痤疮患者常见的后遗症,痤疮和痤疮疤痕都直接损害了患者的外观,影响了患者的身心健康。流行病学显示,大约43%的痤疮患者会有不同程度的疤痕。目前,有多种方法被用于治疗痤疮疤痕,但有些方法价格昂贵、效果不佳,并会引起并发症。近日,发表于Radiother Oncol的一项前瞻性的分脸对照研究旨在评估超脉冲二氧化碳点阵激光联合30%超分子水杨酸治疗痤疮疤痕的疗效和安全性。

研究共纳入了20名面部对称性痤疮疤痕的患者。一侧面部随机使用30%超分子水杨酸联合超脉冲二氧化碳点阵激光治疗,一侧面部仅使用超脉冲二氧化碳点阵激光治疗。采用Echelle d'evaluation clinique des cicatrices d'acne (ECCA)量表来评价治疗前和治疗后3个月的临床疗效,并采用四分法对患者的改善情况进行自我评价。每次治疗后用视觉模拟量表记录疼痛评分,并记录面部的副作用和其他不良反应。

 

结果,所有患者都完成了治疗和随访。三次治疗后,双侧面部痤疮疤痕的ECCA评分都有统计学差异(P < 0.001)。三次治疗后,联合侧的ECCA评分低于仅激光侧的ECCA评分(P = 0.003)。联合侧的患者满意度四分法高于仅激光治疗侧(P = 0.015)。

综上所述,该研究结果表明,超脉冲CO2点阵激光联合30%超分子水杨酸治疗痤疮疤痕的疗效优于单纯激光,患者自我评价联合治疗对痤疮疤痕的改善程度更高,且不增加患者疼痛评分和相关不良反应。

 

原始出处:

 

Na-Hyun Hwang, et al., Effect of the biologically effective dose of electron beam radiation therapy on recurrence rate after keloid excision: A meta-analysis. Radiother Oncol. 2022 Aug;173:146-153. doi: 10.1016/j.radonc.2022.06.003.  

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    2024-05-13 ms6000000013039699 来自河北省

    学习了, 感谢分享

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    2023-01-31 minlingfeng
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    2022-09-11 oliver169
  6. [GetPortalCommentsPageByObjectIdResponse(id=2204457, encodeId=acd3220445edb, content=学习了, 感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=b4aa8440342, createdName=ms6000000013039699, createdTime=Mon May 13 15:59:52 CST 2024, time=2024-05-13, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=1984071, encodeId=af5719840e154, content=<a href='/topic/show?id=e3f464183db' target=_blank style='color:#2F92EE;'>#水杨酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64183, encryptionId=e3f464183db, topicName=水杨酸)], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/cc81592b507031e3cfd8d4c57911d98b/62c22832a9474aea1ca90ca058aebc03.jpg, createdBy=bed5446, createdName=limedical1974, createdTime=Tue Oct 04 08:50:58 CST 2022, time=2022-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1866709, encodeId=d9af1866e095a, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Tue Jan 31 14:50:58 CST 2023, time=2023-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1792963, encodeId=106b1e9296314, content=<a href='/topic/show?id=34211508e37' target=_blank style='color:#2F92EE;'>#Radiother#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15087, encryptionId=34211508e37, topicName=Radiother)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=35fc2500023, createdName=yanjie6253_56072842, createdTime=Mon Mar 06 05:50:58 CST 2023, time=2023-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279829, encodeId=56b712e98291e, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Sun Sep 11 03:50:58 CST 2022, time=2022-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394144, encodeId=9fb2139414400, content=<a href='/topic/show?id=7b29e0460b1' target=_blank style='color:#2F92EE;'>#疤痕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70460, encryptionId=7b29e0460b1, topicName=疤痕)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/qXbLjJB4FSzhQS3C5qQFMJkqicRIJFL6zHFwwhv0I95nzA6xicevQcEica0gk4A58UkbMMriadAgTY2b7N7Yd0ZsQg/132, createdBy=910c2500152, createdName=HinsMax, createdTime=Sun Sep 11 03:50:58 CST 2022, time=2022-09-11, status=1, ipAttribution=)]
    2022-09-11 HinsMax

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