Diabet Med:2型糖尿病患者血糖控制情况对各种感染的发生有何影响?

2016-10-04 MedSci MedSci原创

本研究旨在探究2型糖尿病患者血糖控制对感染发生率的影响。研究人员对比了2014年2型糖尿病患者与非糖尿病患者的感染率,数据来源于英国的一个大型初级保健队列(皇家全科医师学会研究和监测中心数据库)。采用多层次logistic回归分析探讨2型糖尿病对感染的影响,以及血糖控制对上呼吸道感染、支气管炎、流感样疾病,肺炎、肠道传染病、单纯疱疹、皮肤及软组织感染、尿路感染、生殖器和会阴感染的影响。根据患者最近

本研究旨在探究2型糖尿病患者血糖控制对感染发生率的影响。

研究人员对比了2014年2型糖尿病患者与非糖尿病患者的感染率,数据来源于英国的一个大型初级保健队列(皇家全科医师学会研究和监测中心数据库)。采用多层次logistic回归分析探讨2型糖尿病对感染的影响,以及血糖控制对上呼吸道感染、支气管炎、流感样疾病,肺炎、肠道传染病、单纯疱疹、皮肤及软组织感染、尿路感染、生殖器和会阴感染的影响。

根据患者最近的糖化血红蛋白的水平对其进行分层:控制较好组糖化血红蛋白水平<53 mmol/mol(<7%);控制中等糖化血红蛋白水平为53-69 mmol/mol(7-8.5%);控制较差糖化血红蛋白水平>69 mmol/mol(> 8.5%)]。校正了重要的社会人口学因素和患者合并症后评估感染率。

最终研究人员确定了34278名2型糖尿病患者和613052名非糖尿病对照者。结果发现,除单纯疱疹外,2型糖尿病患者其他疾病的感染发生率较高。血糖控制恶化与支气管炎、肺炎皮肤及软组织感染、尿路感染、生殖器和会阴感染的发生率增加有关,但与上呼吸道感染、流感样疾病及肠道传染病或疱疹的发生率增加无关。

总而言之,该研究发现,除单纯疱疹外,本研究所探究的其余感染均为2型糖尿病患者更常见。感染通常为细菌感染,在血糖控制较差的患者中真菌或酵母的感染更为常见。

原始出处:

Hine JL, et al. Association between glycaemic control and common infections in people with Type 2 diabetes: a cohort study. Diabet Med. 2016;doi:10.1111/dme.13205.

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    2016-10-13 1e10c84am36(暂无匿称)

    文章真好,喜欢阅读

    0

  4. 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encodeId=f7aa1403297f, content=学习了,谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Wed Oct 05 08:55:47 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-11 1e10c84am36(暂无匿称)

    好文章,长见识

    0

  5. 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encodeId=f7aa1403297f, content=学习了,谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Wed Oct 05 08:55:47 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-06 忠诚向上

    好好学习

    0

  6. 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  7. 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    2016-10-05 半夏微凉

    学习了,谢谢!

    0

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