Eur Heart J:到侵入性心脏中心距离、急性冠脉造影和血管成形术性能与院外心脏骤停结局相关吗?

2017-04-03 xing.T MedSci原创

由此可见,入住侵入性心脏中心和区域急性CAG/ PCI性能与OHCA患者生存率改善相关,而与到侵入性心脏中心的距离无关。这些结果支持对OHCA患者即刻复苏后治疗进行集中式策略。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,研究人员旨在评价从心脏事件发生地到侵入性心脏中心、急性冠状动脉造影(CAG)/经皮冠状动脉介入治疗(PCI)得到医院层次的治疗(侵入性心脏中心 vs. 地方医院)的距离是否与院外心脏骤停(OHCA)患者生存率相关。

研究人员回顾性地随访了全国的通过丹麦心脏骤停注册中心确认的41186例未经选择的OHCA患者,这些患者在2001-2013之间接受了复苏。

研究人员观察到在接受旁观者心肺复苏(2001年为18%,2013年为60%,P<0.001)、实现自主循环恢复(ROSC)(2001年为10%,2013年为29%,P<0.001)和直接入住侵入性中心(2001年为26%,2013年为45%,P<0.001)的患者比例增加。同时,这些患者的30天生存率从2001年的5%上升到2013年的12%,P<0.001。在达到ROSC的患者中,也有较大比例的患者接受了急性CAG/PCI(2001年为5%,2013年为27%,P<0.001)。在每个区域的患者每年接受了急性CAG/PCI的比例被定义为CAG/PCI指数。

在多变量分析中,以下变量与较低的死亡率相关:直接入住侵入性心脏中心(风险比(HR)为0.91,95%可信区间(CI)为0.89-0.93)、CAG/PCI指数(HR为0.33,95%CI为0.25-0.45)、人口密度超过每平方公里2000人(HR为0.94,95%CI为0.89-0.98)、旁观者心肺复苏(HR为0.97,95%CI为0.95-0.99)、被见证的OHCA(HR为0.87,95%CI为0.85-0.89),而到最近的侵入性中心的距离与生存率无关。

由此可见,入住侵入性心脏中心和区域急性CAG/ PCI性能与OHCA患者生存率改善相关,而与到侵入性心脏中心的距离无关。这些结果支持对OHCA患者即刻复苏后治疗进行集中式策略。

原始出处:


Tinne Tranberg, et al. Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study. Eur Heart J. https://doi.org/10.1093/eurheartj/ehx104

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    2017-04-05 zhaojie88
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  7. [GetPortalCommentsPageByObjectIdResponse(id=2028744, encodeId=a3cd2028e4422, content=<a href='/topic/show?id=b1e1269e5c6' target=_blank style='color:#2F92EE;'>#侵入性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26975, encryptionId=b1e1269e5c6, topicName=侵入性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Sat Jan 27 18:40:00 CST 2018, time=2018-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1990128, encodeId=addf199012894, content=<a href='/topic/show?id=66308965e00' target=_blank style='color:#2F92EE;'>#血管成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89657, encryptionId=66308965e00, topicName=血管成形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Tue Sep 05 00:40:00 CST 2017, time=2017-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004661, encodeId=0a3220046613b, content=<a href='/topic/show?id=4e8a5400816' target=_blank style='color:#2F92EE;'>#成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54008, encryptionId=4e8a5400816, topicName=成形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Fri Nov 24 18:40:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305655, encodeId=a601130565583, content=<a href='/topic/show?id=1787983537c' target=_blank style='color:#2F92EE;'>#院外心脏骤停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98353, encryptionId=1787983537c, topicName=院外心脏骤停)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Wed Apr 05 04:40:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356209, encodeId=34d7135620949, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 05 04:40:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1447185, encodeId=2fa9144e18575, content=<a href='/topic/show?id=dd2f31009da' target=_blank style='color:#2F92EE;'>#冠脉造影#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31009, encryptionId=dd2f31009da, topicName=冠脉造影)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/g?b=oidb&k=l9h0OhA0BicNC4kpEUl4AeA&s=100&t=1587635346, createdBy=61865326685, createdName=李研东, createdTime=Wed Apr 05 04:40:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1494022, encodeId=cd5f149402252, content=<a href='/topic/show?id=3e34949e333' target=_blank style='color:#2F92EE;'>#造影#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94973, encryptionId=3e34949e333, topicName=造影)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=908d9134595, createdName=sodoo, createdTime=Wed Apr 05 04:40:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562471, encodeId=bbe915624e145, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 05 04:40:00 CST 2017, time=2017-04-05, status=1, ipAttribution=)]
    2017-04-05 sodoo
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    2017-04-05 slcumt