Diabetologia:注意了!母亲超重和肥胖对后代也有影响

2017-06-21 MedSci MedSci原创

近日,国际杂志 《Diabetologia》上在线发表一项关于母亲超重和肥胖对后代的研究。研究人员旨在比较1型或2型糖尿病母亲后代患严重窒息相关新生儿并发症的风险,并评估母亲超重/肥胖对这些风险的影响。 这是一项基于人口的研究,包括在1997年至2011年期间瑞典的1343,751名活产单胎婴儿,及5941例和711例婴儿的患1型和2型糖尿病的母亲。研究统计了出生后5分钟低Apgar评分(0-6

近日,国际杂志 《Diabetologia》上在线发表一项关于母亲超重和肥胖对后代的研究。研究人员旨在比较1型或2糖尿病母亲后代患严重窒息相关新生儿并发症的风险,并评估母亲超重/肥胖对这些风险的影响。

这是一项基于人口的研究,包括在1997年至2011年期间瑞典的1343,751名活产单胎婴儿,及5941例和711例婴儿的患1型和2糖尿病的母亲。研究统计了出生后5分钟低Apgar评分(0-6),缺氧缺血性脑病和新生儿癫痫发作95CIOR

糖尿病母亲或1型或2型糖尿病的母亲Apgar评分风险总体较低,分别为0.9%,2.6%和2.1%。通过控制产妇的干扰因素(包括BMI)后,低Apgar评分在1型糖尿病母亲后代风险有所增加(OR2.6795CI2.233.20),但在2型糖尿病母亲后代风险未增加( OR 1.25,95CI 0.66,2.35)。1型和2型糖尿病母亲的后代发生缺氧缺血性脑病或新生儿惊厥的OR值是增加的,分别为(OR3.4195CI2.584.49)和(OR2.5495CI1.135.69)。孕妇超重/肥胖是1型糖尿病母亲和无糖尿病母亲的后代窒息相关新生儿并发症和Apgar评分较低的危险因素。

Apgar评分较低和严重窒息相关新生儿并发症在1型或2型糖尿病母亲的后代中发生的风险升高。孕妇超重/肥胖是一个重要的因素。

原始出处:

Sven Cnattingius, Anna Lindam, Martina Persson,et al. Risks of asphyxia-related neonatal complications in offspring of mothers with type 1 or type 2 diabetes: the impact of maternal overweight and obesity.

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    2017-06-22 龙胆草

    学习谢谢分享

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    2017-06-21 中医痴

    不错的,学习了,谢谢分享!

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    2017-06-21 三生有幸9135

    学习一下谢谢分享

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该研究的目的是评估一个便携,可佩带的,无线人工胰脏系统(糖尿病助理 [DiAs]运行统一安全系统),对1型糖尿病患者在家里夜间以及24/7闭环控制的血糖控制(CLC)模式的有效性。该研究在四个国家6个临床中心进行,共有30例18-66岁I型糖尿病患者参与此研究(43%为女性,96%为非西班牙裔白人,平均I型糖尿病持续时间为19年,平均A1C 7.3%)。该过程包括2周基线传感器增强泵(SAP)时期