Neurology:缺血性卒中后头痛

2019-11-08 xing.T MedSci原创

综上所述,这些数据表明,头痛是缺血性卒中发作时或发作后不久的常见病,可能会导致卒中后头痛。需要更好地了解与缺血性卒中相关的头痛,以确定治疗指南并告知患者。

与缺血性卒中相关的头痛知之甚少。为了获得更多的了解,近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,研究人员系统地回顾了缺血性卒中相关的头痛研究,以评估新发卒中后头痛的患病率和特征。

研究人员检索了Medline和PubMed数据库,总共确定了1812条文献。其中,有50篇文献被纳入本系统评价。20篇文献进行Meta分析和Meta回归。

在缺血性卒中人群中头痛发生占6%–44%。大多数头痛具有紧张型特征,为中度至重度,并逐渐变为慢性。研究人员使用反方差异质性模型进行的荟萃分析得到汇总的患病率为0.14(95%置信区间[CI]为0.07-0.23),且各研究之间存在异质性。Mate回归揭示了患病率与研究位置、来源人群的国家人类发展指数(HDI)和研究质量之间的显著相关性。研究人员发现,与中东和亚洲研究(0.08,95%CI为0.01-0.18)相比,欧洲(0.22,95%CI为0.14–0.30)和北美(0.15,95%CI为0.05–0.26)研究的患病率更高。但是,在每个区域中,来自人类发展指数较高的国家(p=0.03)和具有较高质量的研究(p=0.001)的人群患病率较低。计算得出的原始比值比(OR)显示后循环卒中(合并OR为1.92,95%CI为1.4–2.64;n=7项研究)和女性(合并OR为1.25,95%CI为1.07–1.46;n=11项研究)有关。

综上所述,这些数据表明,头痛是缺血性卒中发作时或发作后不久的常见病,可能会导致卒中后头痛。需要更好地了解与缺血性卒中相关的头痛,以确定治疗指南并告知患者。 

原始出处:

Andrea M. Harriott,et al.Headache after ischemic stroke A systematic review and meta-analysis.Neurology.2019.https://n.neurology.org/content/early/2019/11/06/WNL.0000000000008591

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    2019-11-08 yinhl1978
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    2019-11-08 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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