J Altern Complement Med:糖尿病患者福音,芦荟能降血糖!

2016-07-06 Seven L 译 MedSci原创

根据最近的一项荟萃分析,口服芦荟可以降低前驱糖尿病和2型糖尿病患者的空腹血糖和HbA1c。利福尼亚特拉维斯空军基地格兰特空军医疗中心的William R. Dick药学博士和同事们分析了九项研究的数据,评估口服芦荟的摄入对前驱糖尿病和2型糖尿病患者的空腹血糖和HbA1c的影响。9项研究涉及空腹血糖数据(N = 283),5项研究涉及HbA1c数据N = 89)。3项研究涉及芦荟汁,1项研究使用芦荟

根据最近的一项荟萃分析,口服芦荟可以降低前驱糖尿病和2型糖尿病患者的空腹血糖和HbA1c。

利福尼亚特拉维斯空军基地格兰特空军医疗中心的William R. Dick药学博士和同事们分析了九项研究的数据,评估口服芦荟的摄入对前驱糖尿病和2型糖尿病患者的空腹血糖和HbA1c的影响。9项研究涉及空腹血糖数据(N = 283),5项研究涉及HbA1c数据N = 89)。3项研究涉及芦荟汁,1项研究使用芦荟凝胶,4项研究使用芦荟凝胶,1项研究使用干芦荟乳胶树脂。研究人员测量空腹血糖和HbA1c从基线开始的变化作为加权平均差异。

整个研究中,成年人食用口服芦荟可降低空腹血糖46.6 mg/dL (95% CI, –66.54 to –26.74),降低HbA1c 1.05% (95% CI, –1.78 to –0.33)。Egger统计模型显示空腹血糖相关研究发表偏倚(P = .01),但是HbA1c不存在这种情况(P = .602)。

亚组分析中,排除一项显著更大益处的研究后,结果仍同上,空腹血糖加权平均差为–42.9 mg/dL(95% CI, –63.09 to –22.7),HbA1c加权平均差为–0.98% (95% CI, –1.72 to –0.23)。

人群空腹血糖至少200 mg/dL vs.不足200 mg/dL,摄入口服芦荟的益处增加;这个群体经历了平均空腹血糖降低109.9 mg/dL (95% CI, –142.1 to –77.7)。

研究人员指出,在分析存在一些局限性,包括芦荟产品的使用剂量的不同,时间从4到14周的不同,所有的试验样本量小等。

研究表明,口服芦荟的摄入可降低前驱糖尿病和2型糖尿病患者的空腹血糖和HbA1c,对这类人群是有益的,不过在以后还需要更大规模的前瞻性RCT试验来验证该结果。

原始出处:

Dick WR, et al. Reduction of Fasting Blood Glucose and Hemoglobin A1c Using Oral Aloe Vera: A Meta-Analysis .J Altern Complement Med. 2016;doi:10.1089/acm.2015.0122.

Oral aloe vera may reduce fasting blood glucose in type 2 diabetes.
Healio.July 5, 2016

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    2016-07-12 zsyan
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    2016-09-09 w363522449
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    2016-08-15 xuyong536
  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:19:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125723, encodeId=8024125e23e2, content=这是个令糖尿病患者兴奋的消息, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 21:16:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105739, encodeId=669e105e3924, content=好文,值得学习,赞一个。, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:59:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474010, encodeId=ae6314e4010e3, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Jul 08 04:18:00 CST 2016, time=2016-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606974, encodeId=808e16069e417, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Jul 08 04:18:00 CST 2016, time=2016-07-08, status=1, ipAttribution=)]
    2017-01-30 shizhenshan
  5. 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  6. 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channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:59:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474010, encodeId=ae6314e4010e3, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Jul 08 04:18:00 CST 2016, time=2016-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606974, encodeId=808e16069e417, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Jul 08 04:18:00 CST 2016, time=2016-07-08, status=1, ipAttribution=)]
    2016-09-21 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  7. 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channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:59:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474010, encodeId=ae6314e4010e3, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Jul 08 04:18:00 CST 2016, time=2016-07-08, status=1, ipAttribution=), 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    2016-09-13 舒心和人

    这是个令糖尿病患者兴奋的消息

    0

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    2016-08-27 ylzr123

    好文,值得学习,赞一个。

    0

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近日,微博上一个故事引起了争论。一位患者家属说:“我是糖尿病,你们还给我输糖?糖尿病人绝对不能输葡萄糖”。差点引发一场纠纷,到底是为什么事呢? 这个故事最开始的焦点在于:糖尿病可以用葡萄糖补液吗?但由于不仅仅患者不知道,患者的医生家属也不知道,而且评论的医生连补液里面能不能加胰岛素也搞不清楚,从而引发了新一轮的大战…… 糖尿病患者由于体内胰岛素绝对或相对不足,在输注

PLoS One:糖尿病可增加小动脉闭塞型卒中的复发和不良预后风险

背景:糖尿病(DM)与轻型卒中预后的关系尚不清楚。本研究的目的是调查糖尿病是否与轻型卒中或特定亚型的预后相关。方法:所有轻型缺血性脑卒中患者均来自中国国家卒中登记处,根据TOAS T标准将其分为5种亚型。糖尿病定义为自称医生诊断为糖尿病或在住院或出院时使用降糖药物。随访1年,观察复发性脑卒中、死亡和功能转归。功能预后不良为改良Rankin评分2-6。应用单因素和多因素Logistic回归分析DM和

Diabetes Care:糖尿病嗅探犬可闻出糖尿病气味

剑桥大学的新研究显示,我们的呼吸气体中存在一种化学成分,这种成分可以对I型糖尿病患者低血糖水平发出警告。该研究今天发表在《Diabetes Care》杂志上,这样就可以解释为什么有些狗可以被训练到能够闻出病人的警告信号。Claire Pesterfield患有I型糖尿病,她需要注射胰岛素来控制血糖水平。她有一个金色的拉布拉多犬被慈善医疗检测犬机构训练,当她的血糖水平下降到危险值时训练犬可以发出警告

J Epidemiol Community Health:糖尿病会增加急性MI后死亡风险

近期发表在Journal of Epidemiology Community Health的数据显示,相比非糖尿病患者,糖尿病患者急性心肌梗死后的死亡风险更高。英国利兹医学顾问Chris Gale博士对703920名成人患者(66%为男性)的数据进行了分析。在194万人年的随访中,发生了120568例(17.1%)糖尿病和187875例(26.7%)死亡。患者被分为ST抬高型心肌梗死(STEMI)

PLoS Med:健康的植物性饮食可以降低2型糖尿病风险

近期发表在PLOS Medicine的研究称,摄入植物性饮食可以降低2型糖尿病的风险。哈佛T.H.陈公共健康学院营养系的博士后研究员Ambikas Satija和同事对护士健康研究(1984-2012;女性,n = 69949)、护士健康研究2(1991-2011;女性,n = 90239 )和卫生专业人员随访研究(1986-2010;男人,n = 40539)的数据进行了评估,探究植物性饮食和2

Diabetes Care:新型降脂药物帮助糖尿病患者更好地控制血糖

血液中甘油三酯水平高会增加心脏病风险,还有可能增加2型糖尿病风险。一项发表在国际学术期刊Diabetes Care上的研究首次证明大幅降低糖尿病病人的甘油三酯能够改善他们的胰岛素敏感性,有助于帮助病人控制血糖水平。另外,一种试验性降脂药物Volanesorsen能够显著降低病人整体的糖化血红蛋白并改善胰岛素敏感性和血糖控制。该研究由美国宾夕法尼亚大学Perelman医学院的研究人员完成。&nbs