Crit Care:胸部X线与肺部超声鉴别急性呼吸窘迫综合征的性能比较

2018-08-18 xing.T MedSci原创

由此可见,为了使用柏林定义识别ARDS,胸部X线和肺部超声检查与死亡率同等相关。使用肺部超声的柏林定义有助于识别死亡风险较高的患者,即使这些患者使用胸部X线检查不符合传统的柏林定义。然而,当胸部影像学检查结果不同时,患者的适度重叠检查提示胸部X线和肺部超声检查应该互补而不是互换使用。

对于急性呼吸窘迫综合征(ARDS)的确诊,肺部超声可能是胸片的合理替代方法,但肺部超声对ARDS的诊断性能尚不确定。近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,研究人员分析通过胸部X片(Berlin-CXR)或肺部超声(Berlin-LUS)根据柏林定义来诊断ARDS的临床结局。

这是一项针对重症监护病房(ICU)进行的回顾性观察性研究。该研究纳入了2014年8月至2017年3月入住ICU时需要无创通气或有创通气治疗低氧血症性呼吸衰竭的患者。这些患者在ICU入院时进行了胸部X线和肺部超声检查。研究人员使用Berlin-CXR或Berlin-LUS定义进行了比较,以针对每个定义的患者特征和临床结局来诊断ARDS。ICU和住院死亡率是两种诊断方法的主要结局指标。

研究人员分析了456名首次入院的不同患者。与符合Berlin-CXR定义的216名患者(ICU死亡率为19.4%,住院死亡率为36.1%)相比,符合Berlin-LUS定义的229名患者(ICU死亡率为22.7%,住院死亡率为34.5%);79名符合Berlin-LUS但不符合Berlin-CXR定义的患者(ICU死亡率为21.5%,住院死亡率为29.1%)也有类似的结果。相比之下,符合这两个定义的295名患者的死亡率高于161名未符合任何定义的患者(ICU死亡率为20.0% vs. 12.4%,P=0.041;住院死亡率为34.2% vs. 24.2%,P=0.027)。与Berlin-CXR相比,Berlin-LUS的阳性预测值为0.66(95%置信区间为0.59-0.72),阴性预测值为0.71(0.65-0.77)。在216名符合Berlin-CXR定义的ARDS患者中,150名患者(69.4%)也符合Berlin-LUS定义。

由此可见,为了使用柏林定义识别ARDS,胸部X线和肺部超声检查与死亡率同等相关。使用肺部超声的柏林定义有助于识别死亡风险较高的患者,即使这些患者使用胸部X线检查不符合传统的柏林定义。然而,当胸部影像学检查结果不同时,患者的适度重叠检查提示胸部X线和肺部超声检查应该互补而不是互换使用。

原始出处:

Kay Choong See.et al. Chest radiography versus lung ultrasound for identification of acute respiratory distress syndrome: a retrospective observational study.Critical Care.2018. https://doi.org/10.1186/s13054-018-2105-y

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    2018-08-27 huangshang9812

    哈哈哈,学习了

    0

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    2018-08-20 piaojinhua
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    2018-08-20 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0