Pediatrics:上呼吸道病毒感染增加了儿童中耳炎的风险

2016-04-23 MedSci MedSci原创

近期发表在《儿科学》的研究指出上呼吸道病毒感染,致病菌的定植和缺少母乳喂养增加了1岁之前儿童的急性中耳炎的风险。

近期发表在《儿科学》的研究指出上呼吸道病毒感染,致病菌的定植和缺少母乳喂养增加了1岁之前儿童的急性中耳炎的风险。

研究评估了上呼吸道病毒感染(URI)的发病率和并发症,包括急性中耳炎(AOM)和下呼吸道感染(LRI),评估了细菌-病毒反应,以及遗传和环境危险因素对急性中耳炎发展的影响。

研究人员随访了367名健康的婴儿从出生到1岁时AOM的发展。收集1岁时,6个月和9个月大的鼻咽部样本进行定值菌检测和PCR研究。在任何诊断为病毒性URIs的时候均收集鼻咽部样本。

数据显示305个研究对象发生887次URIs,143个婴儿发生108例AOM。发生AOM的婴儿平均每人每年发生4.7次 URIs,无AOM的婴儿每人每年发生2.3次 URIs(P < 0.002)。

研究发现AOM患儿的致病菌定值率高于无AOM的儿童 (P < .005)。研究结果同时表明母乳喂养可降低儿童URIs和AOM风险 (P < 0.05)。

研究作者德克萨斯大学医学部儿科和病理科医生Chonmaitree 和她的同事写到,卡他莫拉菌伴或不伴其他细菌,都改变了URI (HR = 6.1; 95% CI, 4.04-9.23) 和AOM(HR = 1; 95% CI, 0.62-1.6)的风险,无论是否合并病毒感染,卡他莫拉菌感染都增加了URI的风险。“这些复杂的病毒-细菌反应可能为URI和AOM的发病机制提供线索,这需要更大样本的研究。”David Costill写道。

原始出处:

Viral URI, other factors increase risk for AOM in infants,healio

Chonmaitree T1, Trujillo R2, Jennings K3, et al,Acute Otitis Media and Other Complications of Viral Respiratory Infection.Pediatrics. 2016 Mar 28.


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    2016-04-30 hbwxf
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createdBy=806522309442, createdName=ms5236388012055669, createdTime=Thu Jun 02 05:52:00 CST 2016, time=2016-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637319, encodeId=0508163e319be, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun May 01 17:52:00 CST 2016, time=2016-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=133808, encodeId=c0ca13380831, content=关注值得,学习。赞!好文探究。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Sep 23 20:04:00 CST 2016, time=2016-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122437, encodeId=f25712243efd, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Sep 11 11:09:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122436, encodeId=6c1b122436b6, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Sep 11 11:09:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=104775, encodeId=40d0104e7513, content=深度好文,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Aug 26 14:35:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94933, encodeId=b45994933bd, content=幼儿中耳炎的发生确实于此有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Jul 28 15:10:00 CST 2016, time=2016-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726085, encodeId=fa7c1e260855d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Apr 07 12:52:00 CST 2017, time=2017-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85500, encodeId=246e8550026, content=学习了,好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Wed May 11 11:48:00 CST 2016, time=2016-05-11, status=1, ipAttribution=)]
    2016-09-23 ylzr123

    关注值得,学习。赞!好文探究。

    0

  5. 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content=幼儿中耳炎的发生确实于此有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Jul 28 15:10:00 CST 2016, time=2016-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726085, encodeId=fa7c1e260855d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Apr 07 12:52:00 CST 2017, time=2017-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85500, encodeId=246e8550026, content=学习了,好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Wed May 11 11:48:00 CST 2016, time=2016-05-11, status=1, ipAttribution=)]
    2016-09-11 doctorJiangchao

    继续关注

    0

  6. 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    2016-09-11 doctorJiangchao

    继续学习

    0

  7. 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GetPortalCommentsPageByObjectIdResponse(id=85500, encodeId=246e8550026, content=学习了,好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Wed May 11 11:48:00 CST 2016, time=2016-05-11, status=1, ipAttribution=)]
    2016-08-26 ylzr123

    深度好文,赞一个!!!

    0

  8. 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content=幼儿中耳炎的发生确实于此有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Jul 28 15:10:00 CST 2016, time=2016-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726085, encodeId=fa7c1e260855d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Apr 07 12:52:00 CST 2017, time=2017-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85500, encodeId=246e8550026, content=学习了,好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Wed May 11 11:48:00 CST 2016, time=2016-05-11, status=1, ipAttribution=)]
    2016-07-28 刘煜

    幼儿中耳炎的发生确实于此有关。

    0

  9. 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GetPortalCommentsPageByObjectIdResponse(id=85500, encodeId=246e8550026, content=学习了,好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Wed May 11 11:48:00 CST 2016, time=2016-05-11, status=1, ipAttribution=)]
    2017-04-07 feather89
  10. 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GetPortalCommentsPageByObjectIdResponse(id=85500, encodeId=246e8550026, content=学习了,好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Wed May 11 11:48:00 CST 2016, time=2016-05-11, status=1, ipAttribution=)]
    2016-05-11 stead

    学习了,好好看看

    0