J Clin Periodontol:引导性组织再生治疗深牙周骨缺损26年后的牙齿存活率和临床效果评价

2020-06-26 MedSci原创 MedSci原创

虽然任何牙周治疗的首要目的是去除菌斑及其牙周炎症,但从牙周组织的原始结构和功能方面来说,牙周组织的再生是临床牙周病学的终极挑战。

虽然任何牙周治疗的首要目的是去除菌斑及其牙周炎症,但从牙周组织的原始结构和功能方面来说,牙周组织的再生是临床牙周病学的终极挑战。在这种情况下,引导性组织再生(GTR)和釉基质蛋白用于牙周骨缺损的预测性牙周再生治疗。本研究旨在探讨引导组织再生(GTR)治疗深牙周骨缺损后26年的牙齿存活率和临床长期效果。

来自三项前瞻性临床左右半口对照研究的患者,研究了GTR治疗的结果,在术后21-26年进行了重新评估,并根据几个特定部位和患者相关因素对牙齿情况进行了评估。

研究共纳入50名患者,102个骨缺损。在长达26年后的随访中(中位数为23.3年),52.9%的牙齿仍在原位。拔除牙的中位生存期为13.8年。有糖尿病和/或吸烟史的患者脱落的牙齿明显更多。与1年的情况相比,仍在位的牙齿在26年后没有出现新的median CAL损失。

本研究的数据显示,尽管大多数患者没有一直坚持牙周支持治疗,但超过50%的初诊重度牙周炎的牙齿在GTR治疗后的26年内仍然在位。在大多数牙齿中,GTR后1年获得的CAL可以维持较长时间。

原文出处:

Fabian Cieplik,Tooth survival and clinical outcomes up to 26 years after guided tissue regeneration therapy in deep intra‐bony defects: Follow‐up investigation of three randomized clinical trials. Journal of clinical periodontology, 2020 July. Doi: 10.1111/jcpe.13302

 

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    2021-03-19 feather89
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    2020-08-31 童小孩

    学习了

    0

  4. 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createdBy=11e818060478, createdName=sunyl13, createdTime=Sun Jun 28 06:30:07 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799949, encodeId=0d42e9994959, content=<a href='/topic/show?id=aa99498e21e' target=_blank style='color:#2F92EE;'>#引导性组织再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49872, encryptionId=aa99498e21e, topicName=引导性组织再生)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Fri Jun 26 21:49:59 CST 2020, time=2020-06-26, status=1, ipAttribution=)]
    2020-06-28 lfcmxl
  5. 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createdBy=11e818060478, createdName=sunyl13, createdTime=Sun Jun 28 06:30:07 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799949, encodeId=0d42e9994959, content=<a href='/topic/show?id=aa99498e21e' target=_blank style='color:#2F92EE;'>#引导性组织再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49872, encryptionId=aa99498e21e, topicName=引导性组织再生)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Fri Jun 26 21:49:59 CST 2020, time=2020-06-26, status=1, ipAttribution=)]
    2020-06-28 zhouqu_8
  6. 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createdBy=11e818060478, createdName=sunyl13, createdTime=Sun Jun 28 06:30:07 CST 2020, time=2020-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=799949, encodeId=0d42e9994959, content=<a href='/topic/show?id=aa99498e21e' target=_blank style='color:#2F92EE;'>#引导性组织再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49872, encryptionId=aa99498e21e, topicName=引导性组织再生)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Fri Jun 26 21:49:59 CST 2020, time=2020-06-26, status=1, ipAttribution=)]
    2020-06-28 huagfeg
  7. 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