Hypertension:单纯舒张期高血压或严重损害心肾功能

2014-01-06 黄辛 中国科学报

2013年12月30日,记者从上海交通大学医学院获悉,该院附属瑞金医院及上海市高血压研究所的科研人员发现,中青年单纯性舒张期血压升高将会严重损害患者心肾功能,并引发心血管疾病风险。相关成果已在线发表于《高血压》杂志。 血压分成舒张压和收缩压。收缩压是指人的心脏收缩时动脉内壁的最高压力,亦称“高压”;舒张压就是当人的心脏舒张时,动脉血管弹性回缩时产生的压力,又称“低压”。 研究人员统计分析了瑞金

2013年12月30日,记者从上海交通大学医学院获悉,该院附属瑞金医院及上海市高血压研究所的王继光教授发现,中青年单纯性舒张期血压升高将会严重损害患者心肾功能,并引发心血管疾病风险。相关成果已在线发表于《高血压》杂志。

血压分成舒张压和收缩压。收缩压是指人的心脏收缩时动脉内壁的最高压力,亦称“高压”;舒张压就是当人的心脏舒张时,动脉血管弹性回缩时产生的压力,又称“低压”。

研究人员统计分析了瑞金医院高血压门诊尚未接受降压治疗的患者后发现,60岁以下的中青年高血压患者占了将近一半;而在中青年高血压患者中,43%的患者表现为单纯舒张期血压升高。研究表明,单纯舒张期高血压患者,尽管年纪较轻,但和正常血压的同龄人相比,他们的肾脏功能已受到损害,尿微量白蛋白排泄明显增加。若病情发展为收缩期和舒张期血压都升高时,患者靶器官的损伤会更加明显,表现为左心室肥厚、动脉弹性减退、僵硬度增加等。

研究还发现,在单纯舒张期高血压患者中,青年男性居多,其中饮酒者比例较高,常表现为代谢异常,体重、体重指数、腰围、内脏脂肪指数、24小时心率、血尿酸水平均较正常血压者明显升高。研究人员认为,这些状况常与患者一些不健康的生活方式有关,包括盐摄入过多、吸烟或酗酒、热量摄入过高而体力或体育活动较少。患者还会因长期大量饮用含果糖饮料导致代谢紊乱。

原文出处

Wei FF, Li Y, Zhang L, Xu TY, Ding FH, Staessen JA, Wang JG.Association of Target Organ Damage With 24-Hour Systolic and Diastolic Blood Pressure Levels and Hypertension Subtypes in Untreated Chinese.Hypertension. 2013 Nov 18.

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    2014-09-27 yese
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    2014-01-18 feather89
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    2014-01-07 mayimayizmc

    现在对中青年舒张性高血压越来越重视了。

    0

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