J Periodontol:在日本,牙齿健康与代谢综合征关系的纵向研究

2019-02-06 MedSci MedSci原创

据报道,代谢综合征(MetS)与牙周炎之间存在密切关系。然而,由于只有少数纵向研究探究了二者的关联,但是MetS与牙周炎之间的关联尚未完全阐明。本研究旨在使用纵向分析研究牙周状况与MetS变化之间的关系。2014年接受系统性体检的2,716人中共有985人,2016年接受了2,454人中的754人接受了包括社区牙周指数在内的牙科检查。其中,390名个人在2014年和2016年接受了医疗和牙科检查,

据报道,代谢综合征(MetS)与牙周炎之间存在密切关系。然而,由于只有少数纵向研究探究了二者的关联,但是MetS与牙周炎之间的关联尚未完全阐明。本研究旨在使用纵向分析研究牙周状况与MetS变化之间的关系。

2014年接受系统性体检的2,716人中共有985人,2016年接受了2,454人中的754人接受了包括社区牙周指数在内的牙科检查。其中,390名个人在2014年和2016年接受了医疗和牙科检查,并被纳入和审查。

结果显示,在390名个体中,62名个体(15.9%)的MetS成分阳性数量减少,104名(26.7%)增加。多变量分析确定性别(风险比(RR):0.55,95%置信区间(CI):0.37-0.82,P <0.05),酒精摄入量(RR:2.06,95%CI:1.14-3.73,P <0.05),以及血糖(RR:6.45,95%CI:1.45-27.9,P <0.01)是影响MetS的重要因素。患有持续性/进行性牙周炎的个体中MetS组分的数量高于没有/改善的牙周炎的个体(RR:1.75,95%CI:1.14-2.70,P <0.01))。牙周炎的改善对MetS成分有明显的正向影响,包括高血压(RR:2.14,95%CI:1.03-4.43,P <0.05)和高血糖(RR:2.52,95%CI:1.27-4.98,P <0.01),但对高血压有负面影响。

综上所述,该研究的结果表明,由于患有持续性/进行性牙周炎的患者中MetS成分阳性较多的个体的患病率高于没有/改善牙周炎的患者,因此减少牙周炎可能对预防MetS和MetS具有重要意义。

原始出处:

Sakurai SI, Yamada SI, et al., A longitudinal study on the relationship between dental health and metabolic syndrome in Japan. J Periodontol. 2019 Feb 5. doi: 10.1002/JPER.18-0523. 

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    2019-06-21 feather89
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    2019-02-08 zhouqu_8
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