WCIO:地塞米松和福沙吡坦可以降低DEB TACE术后PES风险

2016-06-16 Seven L 译 MedSci原创

根据介入肿瘤学世界会议的报告,对原发性肝癌(HCC)患者进行药物洗脱珠肝动脉化疗栓塞术 (DEB TACE) 前联合使用Decadron和Emend,可以预防患者治疗后的栓塞后综合征。辛辛那提大学介入放射学助理教授Abouelmagd Makramalla博士和同事对71名进行DEB TAC的HCC患者进行了研究。一共涉及113个操作,所有患者在术前通过静脉注射8 mg of Decadron(地

根据介入肿瘤学世界会议的报告,对原发性肝癌(HCC)患者进行药物洗脱微粒肝动脉化疗栓塞术 (DEB TACE) 前联合使用Decadron和Emend,可以预防患者治疗后的栓塞后综合征。

辛辛那提大学介入放射学助理教授Abouelmagd Makramalla博士和同事对71名进行DEB TACE的HCC患者进行了研究。一共涉及113个操作,所有患者在术前通过静脉注射8 mg of Decadron(地塞米松,Merck)和150 mg of Emend (福沙吡坦, Merck)。研究目标是确定这种用药方案能都降低栓塞后综合征(PES)的风险。PES可以在术后72小时内引起发烧、恶心、呕吐、疼痛等不适。

数据显示,有4.4%(n = 5)的患者入院时有PES,随后DEB TACE治疗;99名患者不需要住院或急诊就诊;9名患者因为非PES原因入院。

研究人员总结说,“门诊进行DEB TACE前使用地塞米松和福沙吡坦治疗是可行的,能降低患者因PES的入院率。”

原始出处:

Young C, et al. Abstract #. Presented at: World Conference on Interventional Oncology; June 9-12, 2016; Boston.

Decadron plus Emend reduces PES after drug eluting bead TACE for HCC
.Healio.June 15, 2016


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    2016-12-05 shanyongle
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    2017-04-17 feather89
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    2016-07-03 grace5700
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