Dermatol Surg:前额注射肉毒杆菌毒素,皮内注射和肌肉注射是否有区别?

2021-09-01 MedSci原创 MedSci原创

近年来,A型肉毒杆菌毒素(BTXA)在美容手术中的应用急剧增加,特别是用于治疗面部皱纹。但是,目前还没有研究客观地评估了BTXA皮内注射对眉毛高度和额肌作用的影响。为此,发表于Dermatol Sur

近年来,A型肉毒杆菌毒素(BTXA)在美容手术中的应用急剧增加,特别是用于治疗面部皱纹。但是,目前还没有研究客观地评估了BTXA皮内注射对眉毛高度和额肌作用的影响。为此,发表于Dermatol Surg的研究调查了不同注射方式下的效果差异。

研究纳入19名女性,15名女性额部接受皮内注射肉毒杆菌毒素(总剂量为8U),14名妇女接受肌肉注射。

 

结果显示,第2周出现最大的抗皱效果,两组的效果持续时间相同。肌肉注射组的眉毛位置在第2周和第4周降低,皮内注射组在整个随访期间保持不变。两组的最大自主眉毛运动量在第2周和第4周有所下降,在第16周恢复。两组的额肌肌电图振幅的变化都延长到第16周。两组受试者对皱纹的主观满意度相似。然而,皮内注射受试者的疼痛感更强。

综上所述,该研究结果表明,皮内注射肉毒杆菌毒素是一种安全有效的改善额部皱纹的方法。

 

原始出处:

 

Yu Jin Kim, et al., Are There Differences Between Intradermal and Intramuscular Injections of Botulinum Toxin on the Forehead? Dermatol Surg. 2020 Dec;46(12):e126-e131. doi: 10.1097/DSS.0000000000002379.

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