Clin Gastroenterol H:肝移植术后ABS患者金属支架的疗效及更佳持续时间如何?

2017-06-18 xing.T MedSci原创

由此可见,单次ERCP放置cSEMS的ABS的解决率似乎与多次ERCP放置PS的报道相当。支架插入时间越长,ABS解决率越高。

肝移植术后最常见的并发症之一是吻合口胆管狭窄(ABS)。内镜下逆行胰胆管造影(ERCP)插入塑料支架(PS)的做法在实现解决狭窄前往往需要多个程序才能完成。到目前为止,在ABS患者的治疗中采用覆膜自膨式金属支架(cSEMS)的研究报道了不同程度的疗效。近日,消化病领域权威杂志Clinical Gastroenterology and Hepatology发表了一篇研究文章,该研究的目的是分析ABS患者采用cSEMS治疗的长期疗效,并确定影响狭窄解决概率的因素。

研究人员通过内镜数据库查询确定了接受cSEMS治疗的ABS肝移植患者。研究人员分析了狭窄解决率、无狭窄间隔时间、狭窄解决的相关因素以及不良结局。

在44例肝移植且出现难治性ABS患者,这些患者接受了ERCP-cSEMS治疗,研究人员观察到33例患者狭窄得到解决(75%)。较长时间的cSEMS插入是与狭窄解决概率增加相关的唯一变量。cSEMS每增加一周,狭窄解决的几率增加20%。在33例初始狭窄解决的患者中,26例(78.8%)患者在整个随访期间保持胆管通畅。最常见的不良结局是cSEMS 发生内部的移位,其有11例患者(25%)发生这一不良结局。

由此可见,单次ERCP放置cSEMS的ABS的解决率似乎与多次ERCP放置PS的报道相当。支架插入时间越长,ABS解决率越高。

原始出处:

Sunguk Jang,et al. Efficacy and optimal duration of metallic stent in the management of refractory anastomotic stricture after liver transplantation. Clinical gastroenterology and hepatology 2017. http://www.cghjournal.org/article/S1542-3565(17)30721-8/fulltext

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    2018-01-07 许安
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    2018-02-07 cy0324
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    2017-11-02 gous
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    2017-06-24 大爰

    学习了谢谢分享!!!

    0

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    2017-06-20 zhwj
  8. [GetPortalCommentsPageByObjectIdResponse(id=2071809, encodeId=fc3520e1809c5, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sun Jan 07 00:36:00 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711087, encodeId=b2de1e110875e, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Mon Apr 09 16:36:00 CST 2018, time=2018-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998918, encodeId=afa6199891805, content=<a href='/topic/show?id=8e2ee5200ee' target=_blank style='color:#2F92EE;'>#移植术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75200, encryptionId=8e2ee5200ee, topicName=移植术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Wed Feb 07 05:36:00 CST 2018, time=2018-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2064135, encodeId=7bea206413527, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Oct 13 01:36:00 CST 2017, time=2017-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926580, encodeId=4aba192658073, content=<a href='/topic/show?id=4c19961e039' target=_blank style='color:#2F92EE;'>#金属支架#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96170, encryptionId=4c19961e039, topicName=金属支架)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a9987, createdName=gous, createdTime=Thu Nov 02 10:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214654, encodeId=6f76214654f3, content=学习了谢谢分享!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jun 24 07:26:40 CST 2017, time=2017-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503631, encodeId=c39c15036319e, content=<a href='/topic/show?id=4f215634296' target=_blank style='color:#2F92EE;'>#持续时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56342, encryptionId=4f215634296, topicName=持续时间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=13e29684821, createdName=zhwj, createdTime=Tue Jun 20 06:36:00 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212407, encodeId=dc0d21240ed5, content=学习啦!谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Jun 18 19:00:29 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212386, encodeId=21e6212386a7, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Sun Jun 18 17:00:28 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 tanxingdoctor

    学习啦!谢谢分享

    0

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    2017-06-18 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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