Urol J:富血小板血浆可显著降低女性细菌性膀胱炎的复发率

2020-10-02 MedSci原创 MedSci原创

复发性细菌性膀胱炎是女性常见的感染疾病,其抗生素治疗备受关注。富血小板血浆具有抗菌和组织修复作用。本研究探究了富血小板血浆作为静脉内治疗预防细菌性膀胱炎复发的效果,研究结果已在线发表于Urol J。

复发性细菌性膀胱炎是女性常见的感染疾病,其抗生素治疗备受关注。富血小板血浆具有抗菌和组织修复作用。本研究探究了富血小板血浆作为静脉内治疗预防细菌性膀胱炎复发的效果,研究结果已在线发表于Urol J。

将30名有细菌性膀胱炎复发史的妇女随机分为两组:1)富血小板血浆组;2)对照组。第一组接受富血小板血浆10 mL,静脉灌注加40 mL正常生理盐水。对照组只接受50 mL正常生理盐水。每周进行一次灌注,持续4周。在最后一次灌注后的2个月和12个月后,分别对参与者进行了问卷调查(膀胱过度活动性尿失禁国际咨询问卷)和尿液培养。

 

结果显示,灌注12个月后,与对照组相比,富血小板血浆组受试者细菌性膀胱炎复发次数显著减少(4对1,P=0.004)。另外,与对照组相比,富血小板血浆组灌注2个月(3.4±2.77对0.006±1.83,P<0.001)和12个月(3.6±2.58对0.66±1.63,P=0.002)后问卷评分有明显改善。灌注后12个月无不良反应。

综上所述,该研究结果表明,富血小板血浆可显著降低细菌性膀胱炎的复发率,灌注后一年内无任何副作用。

 

原始出处:

 

Mahboubeh MirzaeiAzar Daneshpajooh, et al., The Therapeutic Effect of Intravesical Instillation of Platelet Rich Plasma on Recurrent Bacterial Cystitis in Women: A Randomized Clinical Trial. Urol J. 2019 Dec 24;16(6):609-613. doi: 10.22037/uj.v0i0.5239.

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    2020-10-17 Seven-2

    学习

    0

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    2020-10-04 1581f8c42cm

    好学习

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