药物性肝损伤基层诊疗指南(2019年)

2020-10-20 中华医学会 中华全科医师杂志.2020.19(10):868-875.

药物性肝损伤(drug‑induced liver injury DILI),是指由各类处方或非处方的化学药物、生物制剂以及传统中药、天然药、保健品、膳食补充剂(TCM‑NM‑HP‑DS)及

中文标题:

药物性肝损伤基层诊疗指南(2019年)

发布机构:

中华医学会

发布日期:

2020-10-20

简要介绍:

药物性肝损伤(drug‑induced liver injury DILI),是指由各类处方或非处方的化学药物、生物制剂以及传统中药、天然药、保健品、膳食补充剂(TCM‑NM‑HP‑DS)及其代谢产物乃至辅料等所诱发的肝损伤,亦称药物性肝病。在药物使用过程中,因药物本身和/或其代谢产物导致,或由于特殊体质对药物的超敏感性或耐受性降低导致DILI发生,是最常见和最严重的药物不良反应(ADR)之一,临床上可表现为急性或慢性肝病。

 

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评论区 (35)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2092698, encodeId=797d2092698ea, content=谢谢分享,很好的资料, beContent=null, objectType=guider, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29cf4705638, createdName=ye.song, createdTime=Sun Oct 09 18:02:59 CST 2022, time=2022-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1079876, encodeId=39d710e9876a0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Tue Dec 14 10:38:46 CST 2021, time=2021-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073813, encodeId=353410e38132a, content=非常及时, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:44 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073812, encodeId=7fa910e3812e0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:30 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073387, encodeId=520210e33877e, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44a85635952, createdName=ms6000002046600114, createdTime=Wed Nov 24 07:04:56 CST 2021, time=2021-11-24, status=1, ipAttribution=)]
    2022-10-09 ye.song

    谢谢分享,很好的资料

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2092698, encodeId=797d2092698ea, content=谢谢分享,很好的资料, beContent=null, objectType=guider, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29cf4705638, createdName=ye.song, createdTime=Sun Oct 09 18:02:59 CST 2022, time=2022-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1079876, encodeId=39d710e9876a0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Tue Dec 14 10:38:46 CST 2021, time=2021-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073813, encodeId=353410e38132a, content=非常及时, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:44 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073812, encodeId=7fa910e3812e0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:30 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073387, encodeId=520210e33877e, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44a85635952, createdName=ms6000002046600114, createdTime=Wed Nov 24 07:04:56 CST 2021, time=2021-11-24, status=1, ipAttribution=)]
    2021-12-14 湛海深蓝

    学习了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2092698, encodeId=797d2092698ea, content=谢谢分享,很好的资料, beContent=null, objectType=guider, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29cf4705638, createdName=ye.song, createdTime=Sun Oct 09 18:02:59 CST 2022, time=2022-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1079876, encodeId=39d710e9876a0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Tue Dec 14 10:38:46 CST 2021, time=2021-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073813, encodeId=353410e38132a, content=非常及时, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:44 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073812, encodeId=7fa910e3812e0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:30 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073387, encodeId=520210e33877e, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44a85635952, createdName=ms6000002046600114, createdTime=Wed Nov 24 07:04:56 CST 2021, time=2021-11-24, status=1, ipAttribution=)]
    2021-11-25 湛海深蓝

    非常及时

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2092698, encodeId=797d2092698ea, content=谢谢分享,很好的资料, beContent=null, objectType=guider, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29cf4705638, createdName=ye.song, createdTime=Sun Oct 09 18:02:59 CST 2022, time=2022-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1079876, encodeId=39d710e9876a0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Tue Dec 14 10:38:46 CST 2021, time=2021-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073813, encodeId=353410e38132a, content=非常及时, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:44 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073812, encodeId=7fa910e3812e0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:30 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073387, encodeId=520210e33877e, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44a85635952, createdName=ms6000002046600114, createdTime=Wed Nov 24 07:04:56 CST 2021, time=2021-11-24, status=1, ipAttribution=)]
    2021-11-25 湛海深蓝

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2092698, encodeId=797d2092698ea, content=谢谢分享,很好的资料, beContent=null, objectType=guider, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29cf4705638, createdName=ye.song, createdTime=Sun Oct 09 18:02:59 CST 2022, time=2022-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1079876, encodeId=39d710e9876a0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Tue Dec 14 10:38:46 CST 2021, time=2021-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073813, encodeId=353410e38132a, content=非常及时, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:44 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073812, encodeId=7fa910e3812e0, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210630/a3278bbe5aed4440b3b9ed5777256bc6/8ff2539176cc43df9c4b28d473801e23.jpg, createdBy=800a5537993, createdName=湛海深蓝, createdTime=Thu Nov 25 11:54:30 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073387, encodeId=520210e33877e, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44a85635952, createdName=ms6000002046600114, createdTime=Wed Nov 24 07:04:56 CST 2021, time=2021-11-24, status=1, ipAttribution=)]
    2021-11-24 ms6000002046600114

    学习了

    0