ISSN: 1838-7640Theranostics
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Nanotheranostics 2024; 8(4): 473-496. [Abstract] [Full text] [PDF]
Nanotheranostics 2024; 8(4): 458-472. [Abstract] [Full text] [PDF]
International Journal of Biological Sciences
International Journal of Medical Sciences
Global reach, higher impact
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Research Paper
Extracellular vesicles from apoptotic BMSCs ameliorate osteoporosis via transporting regenerative signals
Maojiao Li, Qi Tang, Chengcheng Liao, Zhuo Wang, Siyuan Zhang, Qingqing Liang, Cheng Liang, Xiaodong Liu, Jingyi Zhang, Weidong Tian, Li Liao
Theranostics 2024; 14(9): 3583-3602. doi:10.7150/thno.96174
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Research Paper
A novel selenium analog of HDACi-based twin drug induces apoptosis and cell cycle arrest via CDC25A to improve prostate cancer therapy
Zhiyong Shi, Miaomiao Liu, Xiaowen Zhang, Jingyang Wang, Junwei Zhang, Zeyan Peng, Li Meng, Ruijing Wang, Lihong Guo, Qiang Zhang, Jing Li, Liang Yang, Jie Liu, Yang Xu, Jie Yan, Jianlin Cui, Shan Ren, Yang Gao, Yanming Wang, Zhi Qi
Theranostics 2024; 14(9): 3565-3582. doi:10.7150/thno.92119
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Review
Metronomic chemotherapy in cancer treatment: new wine in an old bottle
Huai-liang Wu, Han-xing Zhou, Li-min Chen, Shu-sen Wang
Theranostics 2024; 14(9): 3548-3564. doi:10.7150/thno.95619
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Research Paper
Single cell analyses reveal the PD-1 blockade response-related immune features in hepatocellular carcinoma
Yao Li, Fengwei Li, Lei Xu, Xiaodong Shi, Hui Xue, Jianwei Liu, Shilei Bai, Yeye Wu, Zhao Yang, Feng Xue, Yong Xia, Hui Dong, Feng Shen, Kui Wang
Theranostics 2024; 14(9): 3526-3547. doi:10.7150/thno.95971
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Research Paper
Targeting endothelial glycolytic reprogramming by tsRNA-1599 for ocular anti-angiogenesis therapy
Xiao-yan Han, Ling-jie Kong, Duo Li, Ming Tong, Xiu-miao Li, Chen Zhao, Qin Jiang, Biao Yan
Theranostics 2024; 14(9): 3509-3525. doi:10.7150/thno.96946
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Research Paper
Deciphering m6A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy
Jiawen Li, Li Wei, Kaifeng Hu, Yunxiang He, Guidong Gong, Qisong Liu, Yue Zhang, Kaiyu Zhou, Junling Guo, Yimin Hua, Jun Tang, Yifei Li
Theranostics 2024; 14(9): 3486-3508. doi:10.7150/thno.95664
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Research Paper
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma
Yu Zhou, Huakan Zhao, Ran Ren, Mingyue Zhou, Jiangang Zhang, Zhijuan Wu, Yu Chen, Juan Lei, Yang Chen, Ying Yu, Yongsheng Li
Theranostics 2024; 14(9): 3470-3485. doi:10.7150/thno.92646
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Research Paper
Developing targeted therapies for neuroblastoma by dissecting the effects of metabolic reprogramming on tumor microenvironments and progression
Wenyi Jin, Yubiao Zhang, Zhijie Zhao, Mingyong Gao
Theranostics 2024; 14(9): 3439-3469. doi:10.7150/thno.93962
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile
Congratulations! Professor Chen has been elected as a member of the Academia Europaea.
- Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
- Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
CFP - Special issue on Molecular Imaging and Theranostics. Guest Editors: Dr. Jianhua Zou, Dr. Jingjing Zhang and Dr. Mengyao Zhao.
Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.
Background: Sorafenib is the standard treatment for advanced hepatocellular carcinoma (HCC), but acquired resistance during the treatment greatly limits its clinical efficiency. Lipid metabolic disorder plays an important role in hepatocarcinogenesis. However, whether and how lipid metabolic reprogramming regulates sorafenib resistance of HCC cells remains vague. Methods: Sorafenib resistant HCC cells were established by continuous induction. UHPLC-MS/MS, proteomics, and flow cytometry were used to assess the lipid metabolism. ChIP and western blot were used to reflect the interaction of signal....
Cancer therapy has moved from single agents to more mechanism-based targeted approaches. In recent years, the combination of HDAC inhibitors and other anticancer chemicals has produced exciting progress in cancer treatment. Herein, we developed a novel prodrug via the ligation of dichloroacetate to selenium-containing potent HDAC inhibitors. The effect and mechanism of this compound in the treatment of prostate cancer were also studied. Methods: The concerned prodrug SeSA-DCA was designed and synthesized under mild conditions. This compound's preclinical studies, including the pharmacokinetics,....
Nanotheranostics is indexed in MEDLINE and PubMed Central ...
Review
Nanomedicine And Nanotheranostics: Special Focus on Imaging of Anticancer Drugs Induced Cardiac Toxicity
Aseem Setia, Randheer Reddy Challa, Bhaskar Vallamkonda, Phanikumarreddy Satti, Abhishesh Kumar Mehata, Vishnu Priya, Senthil Kumar, Madaswamy S. Muthu
Nanotheranostics 2024; 8(4): 473-496. doi:10.7150/ntno.96846
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