期刊: ACTA NEUROPATHOLOGICA, 2023; 146 (3)
The accumulation of proteinaceous inclusions in the brain is a common feature among neurodegenerative diseases such as Alzheimer's disease, Parkinson'......
期刊: ACTA NEUROPATHOLOGICA, 2023; 145 (1)
Mutations in the gene encoding the ubiquitously expressed free radical scavenging enzyme superoxide dismutase-1 (SOD1) are found in 2-6% of amyotrophi......
期刊: ACTA NEUROPATHOLOGICA, 2023; 146 (6)
Multiple sclerosis (MS) is the most frequent inflammatory and demyelinating disease of the CNS. The disease course in MS is highly variable and driven......
期刊: ACTA NEUROPATHOLOGICA, 2023; 145 (1)
Molecular groups of medulloblastoma (MB) are well established. Novel risk stratification parameters include Group 3/4 (non-WNT/non-SHH) methylation su......
期刊: ACTA NEUROPATHOLOGICA, 2023; 145 (5)
Group 4 tumours (MBGrp4) represent the majority of non-WNT/non-SHH medulloblastomas. Their clinical course is poorly predicted by current risk-factors......
期刊: ACTA NEUROPATHOLOGICA, 2023; 146 (2)
Multiple sclerosis (MS) is a highly heterogeneous demyelinating disease of the central nervous system (CNS) that needs for reliable biomarkers to fore......
期刊: ACTA NEUROPATHOLOGICA, 2023; 146 (2)
Parkinson & PRIME;s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Aggravation of sy......
期刊: ACTA NEUROPATHOLOGICA, 2023; 145 (2)
The major neuropathological hallmarks of Alzheimer's disease (AD) are amyloid beta (A beta) plaques and neurofibrillary tangles (NFT), accompanied by ......