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Subtypes of atopic dermatitis: From phenotype to endotype

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (1)

Atopic dermatitis (AD) is a heterogenous disorder and can be classified into different types. Stratification of subtypes may enable personalized medic......

JIF:3.164

Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (3)

Background: Airway epithelium-derived cytokines are critical to provoke and perpetuate type 2 inflammation in asthma. Yet it is poorly understood how ......

JIF:3.164

Individual characteristics and associated factors of hay fever: A largescale mHealth study using AllerSearch

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (3)

Background: The prevalence of hay fever, a multifactorial allergic disease, is increasing. Identifying individual characteristics and associated facto......

JIF:3.164

Regional differences in the incidence of asthma exacerbations in Japan: A heat map analysis of healthcare insurance claims data

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (1)

Background: In Japan, regional differences in asthma mortality have been reported; however, regional differences in asthma exacerbations have not been......

JIF:3.164

Peripheral itch sensitization in atopic dermatitis

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (3)

Atopic dermatitis is a skin disorder caused by skin dryness and barrier dysfunction, resulting in skin inflammation and chronic itch (or pruritus). Th......

JIF:3.164

Early introduction of very small amounts of multiple foods to infants: A randomized trial

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (3)

Background: We investigated whether multiple food allergies could be safely prevented by simultaneously administering very small amounts of multiple f......

JIF:3.164

Neuro-allergology: Mast cellenerve cross-talk

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (3)

Mast cells (MCs) are derived from hematopoietic stem cells in the bone marrow, and their maturation is regulated by the tissue environment, such as th......

JIF:3.164

A phase 3, randomized, double-blind, clinical study to evaluate the long-term safety and efficacy of gefapixant in Japanese adult participants with refractory or unexplained chronic cough

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (4)

Background: In two phase 3, global clinical trials (COUGH-1 and COUGH-2), the P2X3-receptor antagonist gefapixant significantly reduced objective 24-h......

JIF:3.164

Singlet oxygen -derived nerve growth factor exacerbates airway hyperresponsiveness in a mouse model of asthma with mixed inflammation

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (3)

Background: Refractory asthma, which is caused by several factors including neutrophil infiltration is a serious complication of bronchial asthma. We ......

JIF:3.164

Skin barrier defects in atopic dermatitis: From old idea to new opportunity

期刊: ALLERGOLOGY INTERNATIONAL, 2022; 71 (1)

Atopic dermatitis (AD) is the most common chronic skin inflammatory disease, with a profound impact on patients' quality of life. AD varies considerab......

JIF:3.164

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