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LINC01089, suppressed by YY1, inhibits lung cancer progression by targeting miR-301b-3p/HPDG axis

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (6)

Purpose LINC01089 is a newly identified lncRNA and rarely reported in human cancers. Our study aimed to investigate its role in lung cancer. Methods Y......

JIF:5.035

CircRNA hsa_circ_0014130 function as a miR-132-3p sponge for playing oncogenic roles in bladder cancer via upregulating KCNJ12 expression

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (6)

The modern categories of endogenous non-coding RNAs, namely circular RNAs (circRNAs), involved within the carcinogenesis and progression of various hu......

JIF:5.035

LncRNA TUG1 compromised neuronal mitophagy in cerebral ischemia/reperfusion injury by targeting sirtuin 1

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (6)

Background Mitophagy protects against cerebral ischemia/reperfusion (CI/R)-induced neuronal apoptosis via mitochondrial clearance. Although taurine-up......

JIF:5.035

Inhibition of calpain reduces cell apoptosis by suppressing mitochondrial fission in acute viral myocarditis

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (3)

Cardiomyocyte apoptosis is critical for the development of viral myocarditis (VMC), which is one of the leading causes of cardiac sudden death in youn......

JIF:5.035

SARS-CoV-2 Spike protein is not pro-inflammatory in human primary macrophages: endotoxin contamination and lack of protein glycosylation as possible confounders

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (4)

Introduction The inflammatory potential of SARS-CoV-2 Spike S1 (Spike) has never been tested in human primary macrophages (M Phi). Different recombina......

JIF:5.035

3-Nitrobenzanthrone promotes malignant transformation in human lung epithelial cells through the epiregulin-signaling pathway

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (5)

Exposure to environmental and occupational contaminants leads to lung cancer. 3-Nitrobenzanthrone (3-nitro-7H-benz[de]anthracen-7-one, 3-NBA) is a pot......

JIF:5.035

Pulmonary fibrosis model using micro-CT analyzable human PSC-derived alveolar organoids containing alveolar macrophage-like cells

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (4)

Human lung organoids (hLOs) are useful for disease modelling and drug screening. However, a lack of immune cells in hLOs limits the recapitulation of ......

JIF:5.035

27-Hydroxycholesterol is a specific factor in the neoplastic microenvironment of HCC that causes MDR via GRP75 regulation of the redox balance and metabolic reprogramming

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (2)

Objective Due to the tissue specificity of the liver, long-term exposure to a high concentration of 27-hydroxycholesterol (27HC) is a special characte......

JIF:5.035

Programming changes of hippocampal miR-134-5p/SOX2 signal mediate the susceptibility to depression in prenatal dexamethasone-exposed female offspring

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (1)

Depression is a neuropsychiatric disorder and has intrauterine developmental origins. This study aimed to confirm the depression susceptibility in off......

JIF:5.035

Sevoflurane impairs m6A-mediated mRNA translation and leads to fine motor and cognitive deficits

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (2)

Clinical surgical practices have found that children who undergo multiple anesthesia may have an increased risk of deficiencies in cognition and fine ......

JIF:5.035

Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (6)

Purpose Long non-coding RNAs (lncRNAs) play vital roles in tumor progression and resistance. Ovarian cancer (OC), a common gynecological cancer, is as......

JIF:5.035

Mechanistic insights into HuR inhibitor MS-444 arresting embryonic development revealed by low-input RNA-seq and STORM

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (6)

With improvements in the survival rate of patients with cancer, fertility maintenance has become a major concern in terms of cancer treatment for wome......

JIF:5.035

Mesenchymal stem cell-derived extracellular vesicles prevent glioma by blocking M2 polarization of macrophages through a miR-744-5p/TGFB1-dependent mechanism

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (4)

Aim Our current study is conducted with intention to explore the regulatory mechanism of mesenchymal stem cell (MSC)-derived extracellular vesicle (EV......

JIF:5.035

Lipopolysaccharide facilitates immune escape of hepatocellular carcinoma cells via m6A modification of lncRNA MIR155HG to upregulate PD-L1 expression

期刊: CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (6)

Recent studies have suggested that the initiation and progression of hepatocellular carcinoma (HCC) are closely associated with lipopolysaccharide (LP......

JIF:5.035

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