The latest WHO classification of tumors of the digestive system (2019) has introduced new concepts for the stratification of intraductal neoplasms of ......
Ductal adenocarcinoma is the most common tumor of the pancreas. Although relatively rare, it poses one of the greatest oncological challenges because ......
Whereas predictive immunohistochemistry has represented a core element of breast cancer classification for decades, predictive molecular pathology, wi......
The 2017 WHO classification of pituitary tumors is still based on structural analyses and expression of various pituitary hormones. Three innovations ......
The rapid development of molecular technologies and targeted therapies has fostered the implementation of specialized tumor conferences, known as mole......
Metastatic castration-resistant prostate cancer (mCRPC) is considered as the final stage of the disease with limited therapeutic options to date. In t......
While patients with clinico-radiologically diagnosed resectable pancreatic cancer usually undergo surgery without preoperative cytological or histopat......
Deficient mismatch repair (dMMR) and microsatellite instability (MSI) have therapeutic relevance not only for colorectal carcinomas but also for carci......
The enormous increase in sequencing capacity due to the development of next generation sequencing technologies opens up new opportunities in the field......
Background In Germany pancreas transplants are performed in only a few selected and specialized centres, usually combined with a kidney transplant. Kn......
The development of the WHO classification of tumors of the breast is driven by new knowledge from research whose translation into daily practice is co......
