期刊: PHARMACOLOGICAL RESEARCH, 2023; 196 ()
Microglia are first responders to acute brain insults and initiate neuroinflammation to drive secondary tissue injury. Yet the key molecular switches ......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 196 ()
As depression is projected to become the leading mental disease burden globally by 2030, understanding the underlying pathology, as well as screening ......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 197 ()
Small nucleolar RNA host gene 15 (SNHG15) plays an oncogenic role in many cancers. However, the role of SNHG15 in bladder cancer (BLCA) remains unclea......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 198 ()
Carrimycin is a potential immune-regulating agent for sepsis in patients with tumors. In this study, we inves-tigated its effects on inflammation and ......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 187 ()
Over the past few decades, the treatment of atherosclerotic cardiovascular disease has mainly been through an LDL lowering strategy and treatments tar......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 187 ()
Neuropathic pain is a common health problem resulting in exacerbated response to noxious and non noxious stimuli, as well as impaired emotional and co......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 187 ()
Lipoxin A4 (LXA4) is one of the specialized pro-resolving lipid mediators proved to suppress the progression of atherosclerosis in vivo, but its clini......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 187 ()
The Mediterranean diet (MD) is one of the healthiest ones and is associated with a lower incidence of cardio-vascular and cerebrovascular diseases as ......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 188 ()
Cancer drug development is hindered by high clinical attrition rates, which are blamed on weak predictive power by preclinical models and limited repl......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 191 ()
Oxidative stress (OS) is a chemical imbalance between an oxidant and an antioxidant, causing damage to redox signaling and control or causing molecula......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 193 ()
A potential role of berberine, a benzyl isoquinoline alkaloid, in cancer therapy is apparent. Its underlying mechanisms of berberine against breast ca......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 194 ()
An emerging but less explored shared pathophysiology across microbiota-gut-brain axis disorders is aberrant miRNA expression, which may represent nove......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 195 ()
Liver injury is a common pathological process characterized by massive degeneration and abnormal death of liver cells. With increase in dead cells and......
期刊: PHARMACOLOGICAL RESEARCH, 2023; 197 ()
In the aftermath of tissue injury or infection, an efficient resolution mechanism is crucial to allow tissue healing and preserve appropriate organ fu......