Background Despite multiple treatment advances for castration-resistant prostate cancer (CRPC), there are currently no curative therapies and patients......
Background Metastatic prostate cancer lesions in the skeleton are frequently characterized by excessive formation of bone. Prostate cancer cells secre......
Background The optimal interval for repeat biopsy during active surveillance (AS) for prostate cancer is yet to be defined. This study examined whethe......
Background Despite the rapidly evolving therapeutic landscape, immunotherapy has demonstrated limited activity in prostate cancer. A greater understan......
Background: The numbers needed to image to identify pelvic lymph node and/or distant metastases in newly diagnosed prostate cancer (PCa) patients acco......
Background: Previously we reported that arsenic and estrogen cause synergistic effects in the neoplastic transformation of human prostate epithelial c......
Background Docetaxel-related adverse events (AEs) such as neutropenia and febrile neutropenia (FN) can be life-threatening. A previous in vivo study r......
Background The landscape of somatic mutations in prostate cancer (PCa) has quickly evolved over the past years. Results This evolution was in part due......
Background Interleukin-6 (IL-6) is a pleiotropic cytokine that confers androgen-independence and aggressiveness in prostate cancer (PCa); however, the......
Introduction and objectives Holmium laser enucleation of prostate (HoLEP) represents one of the most studied surgical techniques for benign prostatic ......
Introduction The 2021 Coffey-Holden Prostate Cancer Academy (CHPCA) Meeting, Prostate Cancer Research in the 21st Century, was held virtually, from Ju......
Aim Mutation occurs in the prostate cell genes, leading to abnormal prostate proliferation and ultimately cancer. Prostate cancer (PC) is one of the m......
Background To validate the importance of recently established adverse histopathology features (cribriform pattern and intraductal carcinoma) as contra......
Background We aimed to systematically identify novel susceptible factors related to the occurrence and development of chronic prostatitis/chronic pelv......
Background Germline and somatic mutations in DNA damage repair genes (DDRg) are now recognized as new biomarkers for the management of metastatic pros......
