筛选条件 共查询到61条结果
排序方式
Repurposing Chloroquine Analogs as an Adjuvant Cancer Therapy

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (2)

Background: Drug repurposing is emerging as an attractive strategy with lower attrition rate, lower cost and shorter timeframe than traditional drug d......

Natural Product as Substrates of ABC Transporters: A Review

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (2)

Background: To date, many compounds extracted from natural products have anti -tumor activity, such as citronellol, ellagitannin-containing pomegranat......

Reposition of the Fungicide Ciclopirox for Cancer Treatment

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (2)

Background: Ciclopirox (CPX), a broad-spectrum fungicide, has been widely used to treat fungal infection on the skin and nails for decades. Recent pre......

Next Generation Sequencing in the Management of Leptomeningeal Metas-tases of Non-Small Cell Lung Cancer: A Case Report and Literature Re-view

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)

Case Presentation: We report a 39-year-old male NSCLC patient with negative molecular testing results in the lung cancer tissue sample. The patient de......

Combining PD-1 Inhibitor with VEGF/VEGFR2 Inhibitor in Chemothera-py: Report of a Patient with End-Stage Cholangiocarcinoma and Review of Literature

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)

Background: Cholangiocarcinoma is the second-largest liver cancer, and develops from the biliary epithelium, where it discretely progresses. Unfortuna......

Expression and Clinical Significance of Microtubule-Actin Cross-Linking Factor 1 in Serous Ovarian Cancer

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)

Background: Ovarian Cancer (OC) remains the first leading cause of gynecologic malignancy. The survival rate from Serous Ovarian Cancer (SOC) is very ......

Immunological Mechanism and Clinical Application of PAMP Adjuvants

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)

Background: The host innate immune system can recognize Pathogen-Associated Molecular Patterns (PAMPs) through Pattern Recognition Receptors (PRRs), t......

Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Con- trolling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)

Results: After inhibiting autophagy of HCC-LM3 cells, the inhibitory effect of Bufalin on adhesion, migration and invasion of HCC-LM3 cells was signif......

Construction and Validation of a Nomogram for Predicting Progres- sion-Free Survival in Patients with Early-Stage Testicular Germ Cell Tu-mor

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)

Results: A total of 110 and 62 patients with TGCT were included in the training cohort and validation cohort, respectively. Lymphatic Vascular Invasio......

Expression of B Cell Translocation Gene 1 Protein in Colon Carcinoma and its Clinical Significance

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)

Background: Colon cancer is one of the most common malignant tumors, and B cell Translocation Gene (BTG)1 is involved in the occurrence and developmen......

Lentiviral-Mediated Beclin-1 Overexpression inhibits Cell Proliferation and Induces Autophagy of Human Esophageal Carcinoma Eca109 Cell Xenograft in Nude Mice

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)

Background: Esophageal carcinoma is one of the common malignant tumors in digestive tract. BECLIN-1 is a key gene that regulates autophagy, and its ab......

SOX4 Serves an Oncogenic Role in the Tumourigenesis of Human Breast Adenocarcinoma by Promoting Cell Proliferation, Migration and inhibiting Apoptosis

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)

Background: Breast cancer is among the most common malignant cancers worldwide, and breast adenocarcinoma in glandular tissue cells has excessive meta......

Novel Selective Histone Deacetylase 6 (HDAC6) Inhibitors: A Patent Review (2016-2019)

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)

Background: Many human diseases are associated with dysregulation of HDACs. HDAC6 exhibits deacetylase activity not only to histone protein but also t......

Alkaloids as Anticancer Agents: A Review of Chinese Patents in Recent 5 Years

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)

Background: In recent years, many novel alkaloids with anticancer activity have been found in China, and some of them are promising for developing as ......

The JPJDF has Synergistic Effect with Fluoropyrimidine in the Maintenance Therapy for Metastatic Colorectal Cancer

期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (3)

Background: Maintenance chemotherapeutic regimen with low toxicity is needed for metastatic colorectal cancer. A recent patent has been issued on the ......

共61条页码: 1/5页15条/页