期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (2)
Background: Drug repurposing is emerging as an attractive strategy with lower attrition rate, lower cost and shorter timeframe than traditional drug d......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (2)
Background: To date, many compounds extracted from natural products have anti -tumor activity, such as citronellol, ellagitannin-containing pomegranat......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (2)
Background: Ciclopirox (CPX), a broad-spectrum fungicide, has been widely used to treat fungal infection on the skin and nails for decades. Recent pre......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)
Case Presentation: We report a 39-year-old male NSCLC patient with negative molecular testing results in the lung cancer tissue sample. The patient de......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)
Background: Cholangiocarcinoma is the second-largest liver cancer, and develops from the biliary epithelium, where it discretely progresses. Unfortuna......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)
Background: Ovarian Cancer (OC) remains the first leading cause of gynecologic malignancy. The survival rate from Serous Ovarian Cancer (SOC) is very ......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)
Background: The host innate immune system can recognize Pathogen-Associated Molecular Patterns (PAMPs) through Pattern Recognition Receptors (PRRs), t......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)
Results: After inhibiting autophagy of HCC-LM3 cells, the inhibitory effect of Bufalin on adhesion, migration and invasion of HCC-LM3 cells was signif......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2021; 16 (1)
Results: A total of 110 and 62 patients with TGCT were included in the training cohort and validation cohort, respectively. Lymphatic Vascular Invasio......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)
Background: Colon cancer is one of the most common malignant tumors, and B cell Translocation Gene (BTG)1 is involved in the occurrence and developmen......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)
Background: Esophageal carcinoma is one of the common malignant tumors in digestive tract. BECLIN-1 is a key gene that regulates autophagy, and its ab......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)
Background: Breast cancer is among the most common malignant cancers worldwide, and breast adenocarcinoma in glandular tissue cells has excessive meta......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)
Background: Many human diseases are associated with dysregulation of HDACs. HDAC6 exhibits deacetylase activity not only to histone protein but also t......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (1)
Background: In recent years, many novel alkaloids with anticancer activity have been found in China, and some of them are promising for developing as ......
期刊: RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020; 15 (3)
Background: Maintenance chemotherapeutic regimen with low toxicity is needed for metastatic colorectal cancer. A recent patent has been issued on the ......