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Clinical significance of multi-slice spiral CT, MRI combined with gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (10)

Purpose To explore the application value of multi-slice spiral CT (MSCT), magnetic resonance imaging (MRI) combined with gastric contrast-enhanced ult......

Circ_03955 promotes pancreatic cancer tumorigenesis and Warburg effect by targeting the miR-3662/HIF-1 alpha axis

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (9)

Objectives Former studies found that circRNAs play an important part in the occurrence of a variety of malignant biological characteristics that are c......

Effects of PIM3 in prognosis of colon cancer

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (10)

Purpose PIM kinase is called proto-oncogene, but there are less research on PIM family in colon cancer. This study was designed to explore the prognos......

Investigation on potential biomarkers of hyperprogressive disease (HPD) triggered by immune checkpoint inhibitors (ICIs)

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (9)

Purpose This project aimed to survey the clinical characteristics and survivals of hyperprogressive disease (HPD) mediated by immune checkpoint inhibi......

CIP2A silencing alleviates doxorubicin resistance in MCF7/ADR cells through activating PP2A and autophagy

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (8)

Background Cancerous inhibitor of protein phosphatase 2A (CIP2A) plays a critical role in the pathogenesis of various types of cancer. Here, we invest......

COL4A1, negatively regulated by XPD and miR-29a-3p, promotes cell proliferation, migration, invasion and epithelial-mesenchymal transition in liver cancer cells

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (10)

Objective Collagen type IV alpha 1 (COL4A1) exerts tumor-promoting functions in several tumors. However, its role in liver cancer remains not fully un......

Knockdown of long non-coding RNA RP11-297P16.3 inhibits the migration and invasion of laryngeal squamous carcinoma cells

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (10)

Purpose Laryngeal cancer has a poor prognosis when progressing to an advanced stage with limited treatment options. Therefore, understanding the under......

Mutations in chronic myelomonocytic leukemia and their prognostic relevance

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (9)

Chronic myelomonocytic leukemia (CMML) is a hematologic malignancy that overlaps with myeloproliferative neoplasms (MPN) and myelodysplastic syndromes......

Gene mutations in acute promyelocytic leukemia early death in patients treated with arsenic trioxide alone

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, 2021; 23 (10)

Purpose APL patients have recurrent alterations in FLT3, WT1, NRAS and KRAS. Gene mutations have a strong potential for involvement in pathogenesis an......

Recommended procedures and responsibilities for radiosurgery (SRS) and extracranial stereotactic body radiotherapy (SBRT): report of the SEOR in collaboration with the SEFM

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, ; ()

Today, patient management generally requires a multidisciplinary approach. However, due to the growing knowledge base and increasing complexity of Med......

Curcumin suppresses tumor growth of gemcitabine-resistant non-small cell lung cancer by regulating lncRNA-MEG3 and PTEN signaling

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, ; ()

Background Lung cancer is one of the most aggressive malignancies and the efficacy of chemotherapy or concurrent chemoradiation is limited in clinical......

Dosage of anti-PD-1 monoclonal antibodies: a cardinal open question

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, ; ()

Discovery and clinical development of monoclonal antibodies with the ability to interfere in the regulation of the immune response have significantly ......

Peripheral blood T-cell receptor repertoire as a predictor of clinical outcomes in gastrointestinal cancer patients treated with PD-1 inhibitor

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, ; ()

Background Identifying valid biomarkers for patient selection impressively promotes the success of anti-PD-1 therapy. However, the unmet need for biom......

UCHL3 promotes aerobic glycolysis of pancreatic cancer through upregulating LDHA expression

期刊: CLINICAL & TRANSLATIONAL ONCOLOGY, ; ()

Background Aerobic glycolysis has a pivotal role in the carcinogenic process. The current understanding of the functional role and mechanism of UCHL3-......

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