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Progress of Stimuli-Responsive Nanoscale Metal Organic Frameworks as Controlled Drug Delivery Systems

期刊: CURRENT DRUG DELIVERY, 2021; 18 (3)

Background: Development of controlled drug delivery systems can improve the pharma-cokinetic characteristics of drug molecules in the human body, ther......

Topical Melatonin Niosome Gel for the Treatment of 5-FU-Induced Oral Mucositis in Mice

期刊: CURRENT DRUG DELIVERY, 2021; 18 (2)

Background: Oral mucositis, one of the most common complications of 5-Fluorouracil (5-FU) treatment, leads to several problems, including pain, diarrh......

Release Characteristics of an Essential Oil Component Encapsulated with Cyclodextrin Shell Matrices

期刊: CURRENT DRUG DELIVERY, 2021; 18 (4)

Background: Essential oils are poor aqueous solubility and high volatility compounds. The encapsulation of essential oils with Cyclodextrins (CDs) can......

Formulation, Characterization and Pharmacokinetics of Long-acting Ceftiofur Hydrochloride Suspension

期刊: CURRENT DRUG DELIVERY, 2021; 18 (2)

Objective: A ceftiofur hydrochloride long-acting oily suspension with no irritation was prepared by testing and optimizing the types and amounts of or......

Hyaluronic Acid/Parecoxib-Loaded PLGA Microspheres for Therapy of Temporomandib ular Disorders

期刊: CURRENT DRUG DELIVERY, 2021; 18 (2)

Objective: This study aimed to fabricate Hyaluronic Acid (HA)/parecoxib-loaded PLGA microspheres for the treatment of Temporomandibular Disorders (TMD......

Solid Self-Emulsifying Drug Delivery System (Solid SEDDS) for Testosterone Undecanoate: In Vitro and In Vivo Evaluation

期刊: CURRENT DRUG DELIVERY, 2021; 18 (5)

Objective: The current study aimed to investigate the potential of Solid Self-Emulsifying Drug Delivery Systems (solid SEDDS) loaded with Testosterone......

Mesoporous Bioactive Glass Scaffold Delivers Salvianolic Acid B to Promote Bone Regeneration in a Rat Cranial Defect Model

期刊: CURRENT DRUG DELIVERY, 2021; 18 (3)

Background: Mesoporous Bioactive Glass (MBG) has been widely studied because of its excellent histocompatibility and degradability. However, due to th......

Comparative Evaluation of the Transdermal Permeation Effectiveness of Fu's Cupping Therapy on Eight Different Types of Model Drugs

期刊: CURRENT DRUG DELIVERY, 2021; 18 (4)

Background: Overcoming the skin barrier to achieve the transdermal penetration of drugs across the Stratum Corneum (SC) remains a significant challeng......

Recent Developments in the Principles, Modification and Application Prospects of Functionalized Ethosomes for Topical Delivery

期刊: CURRENT DRUG DELIVERY, 2021; 18 (5)

Transdermal drug delivery helps to circumvent the first-pass effect of drugs and to avoid drug-induced gastrointestinal tract irritation, compared wit......

Study on the Slow-Release Mometasone Furoate Injection of PLGA for the Treatment of Knee Arthritis

期刊: CURRENT DRUG DELIVERY, 2021; 18 (3)

Purpose: The purpose of this study is to develop a new PLGA based formulation for microspheres, which aims to release mometasone furoate for one month......

Development and Biocompatibility Analysis of NBD Peptide Sustained-Release Microsphere Scaffold Nanoparticle SP-Sr-CaS/NBD

期刊: CURRENT DRUG DELIVERY, 2021; 18 (4)

Background: In clinical treatment, it is difficult to carry out effective bone tissue transplantation and anti-inflammatory treatment at the same time......

Investigation on the Preparation, Characteristics, and Controlled Release Model of Paeonol-Loaded Liposome in Carbomer Hydrogel

期刊: CURRENT DRUG DELIVERY, 2020; 17 (2)

Objective: Paeonol is a phenolic compounce that is volatile. In order to decrease its volatility and achieve controlled release. paeonol-loaded liposo......

Realgar Nanoparticles Inhibit Migration, Invasion and Metastasis in a Mouse Model of Breast Cancer by Suppressing Matrix Metalloproteinases and Angiogenesis

期刊: CURRENT DRUG DELIVERY, 2020; 17 (2)

Background: Realgar, a traditional Chinese medicine. has shown antitumor efficacy in several tumor types. We previously showed that realgar nanopartic......

Novel Phospholipid-Based Labrasol Nanomicelles Loaded Flavonoids for Oral Delivery with Enhanced Penetration and Anti-Brain Tumor Efficiency

期刊: CURRENT DRUG DELIVERY, 2020; 17 (3)

Background: Owing to the rich anticancer properties of flavonoids, there is the need for their incorporation into delivery vehicles like nanomicelles ......

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