Structural Study of a New MbtI-Inhibitor Complex: Towards an Optimized Model for Structure-Based Drug Discovery

Mori, M; Villa, S; Chiarelli, LR; Meneghetti, F; Bellinzoni, M

Bellinzoni, M (通讯作者)，Univ Paris Cite, Inst Pasteur, Unite Microbiol Struct, CNRS UMR3528, F-75015 Paris, France.

PHARMACEUTICALS, 2023; 16 (11):

Abstract

MbtI from Mycobacterium tuberculosis (Mtb) is a Mg2+-dependent salicylate synthase, belonging to the chorismate-utilizing enzyme (CUE) family. As a fu......

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