Daam2 driven degradation of VHL promotes gliomagenesis

Zhu, WY; Krishna, S; Garcia, C; Lin, CCJ; Mitchell, BD; Scott, KL; Mohila, CA; Creighton, CJ; Yoo, SH; Lee, HK; Deneen, B

Deneen, B (reprint author), Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA.; Deneen, B (reprint author), Baylor Coll Med, Integrat Mol & Biomed Sci Grad Program, Houston, TX 77030 USA.; Lee, HK (reprint author), Baylor Coll Med, Dept Pedi

ELIFE, 2017; 6 ( ):

Abstract

Von Hippel-Landau (VHL) protein is a potent tumor suppressor regulating numerous pathways that drive cancer, but mutations in VHL are restricted to li......

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