Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of alpha-tocopheryl succinate-based polyphosphoester copolymers

Chen, FQ; Zhang, JM; Fang, XF; Yu, H; Liu, YL; Li, H; Wang, YT; Chen, MW

Chen, MW (reprint author), Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2017; 38 (6): 859

Abstract

P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) is a major obstacle in achieving the therapeutic benefits of paclitaxel (PTX) in the treatme......

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