CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies

Gomes-Silva, D; Srinivasan, M; Sharma, S; Lee, CM; Wagner, DL; Davis, TH; Rouce, RH; Bao, G; Brenner, MK; Mamonkin, M

Mamonkin, M (reprint author), Houston Methodist Hosp, 1102 Bates St,Suite FC1770, Houston, TX 77030 USA.; Mamonkin, M (reprint author), Texas Childrens Hosp, Baylor Coll Med, 1102 Bates St,Suite FC1770, Houston, TX 77030 USA.

BLOOD, 2017; 130 (3): 285

Abstract

Extending the success of chimeric antigen receptor (CAR) T cells to T-cell malignancies is problematic because most target antigens are shared between......

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