SLC5A3-Dependent Myo-inositol Auxotrophy in Acute Leukemia

Wei, YL; Huang, YH; Skopelitis, DS; Iyer, SV; Costa, ASH; Yang, ZL; Kramer, M; Adelman, ER; Klingbeil, O; Demerdash, OE; Polyanskaya, SA; Chang, K; Goodwin, S; Hodges, E; McCombie, WR; Figueroa, ME; Vakoc, CR

Vakoc, CR (通讯作者),Cold Spring Harbor Lab, 1 Bungtown Rd, Cold Spring Harbor, NY 11724 USA.

CANCER DISCOVERY, 2022; 12 (2): 450

Abstract

An enhanced requirement for nutrients is a hallmark property of cancer cells. Here, we optimized an in vivo genetic screening strategy in acute myeloi......

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